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Uni Prot Protein Name Long Description Canonical Function GO Moonlighting Function GO Moon Organism Human Disease Drugs Induction PDBs PDB UniProt Models Reference
P37198 Nuclear pore glycoprotein p62 Essential component of the nuclear pore complex. The N-terminal is probably invo More ... GO:0005642; C:annulate lamellae; IEA:Ensembl.
GO:0005813; C:centrosome; IDA:UniP More ... 		The C-terminal is probably involved in protein-protein interaction via coiled-co More ... GO:0003674 molecular_function GO:0005198 structural molecule activity
GO:001705 More ... 		Homo sapiens Infantile striatonigral degeneration (SNDI) (omim:271930) 5ijn_H/N/T/Z (100), 5ijo_H/N/T/Z (100), 7per_H/N/T/Z (100), 7r5j_J0/J1/J2/J3/J4 More ... Phyre 26791761
P37271 Phytoene synthase EC:2.5.1.32 Carotenoid metabolism GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
GO:0004310; F:farnesy More ... 		Catalyzes committing reactions for diterpene synthesis (C40); over or underexpre More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0003824; F:ca More ... 		Arabidopsis thaliana Phyre 11842148
P37282 60 kDa chaperonin Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ... 		Binding to invertase, a Hyperglycosylated mannoprotein from Saccharomyces cerevi More ... GO:0008150 biological_process
GO:0022610 biological adhesion
GO:0003674 molecula More ... 		Lactococcus lactis 4v4o_A(64) Phyre 17379720
P37475 Stage II sporulation protein E Dephosphorylates SpoAAP GO:0042601; C:endospore-forming forespore; IDA:CACAO.
GO:0016021; C:integral com More ... 		Binds to FtsZ GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Bacillus subtilis 3t91_A(100) 3t91_A/B (100), 3t9q_A/B (100), 5mqh_A (100), 5ucg_A/B/C/D/E (100) Phyre 22014899
P37887 Cysteine synthase Cysteine synthase, enzyme O-acetyl-serine + H2S = cysteine + acetate Amino-acid More ... GO:0005737; C:cytoplasm; IBA:GO_Central.
GO:0004124; F:cysteine synthase activit More ... 		Transcriptional regulator regulates activity of CymR transcription factor forms More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Bacillus subtilis 2egu_A(84) Phyre 17056751
P38011 Guanine nucleotide-binding protein subunit beta-like protein Component of the 40S (small) ribosomal subunit GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
GO:0001965; F:G-protei More ... 		Scaffold in cytoplasmic signal transduction pathways.
Involved in the negative r More ... 		GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Saccharomyces cerevisiae 3frx_A(100) 1trj_A (100), 3frx_A/B/C/D (100), 3j6x_RA (100), 3j6y_RA (100), 3j77_RC (100), 3 More ... Phyre 17584887
P38879 Nascent polypeptide-associated complex subunit alpha Component of the nascent polypeptide-associated complex (NAC), a dynamic compone More ... GO:0005854; C:nascent polypeptide-associated complex; IDA:SGD.
GO:0005634; C:nuc More ... 		Also be involved in transcription regulation and in the ribosome biogenesis. GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Saccharomyces cerevisiae 1tr8.1.A(36) Phyre 25850291
P38936 P21 P21: Inhibition of cyclin-dependent kinase activity, preventing phosphorylation More ... GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:BHF-UCL.
G More ... 		Activation of Cdk GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens brain tumor (omim:116899) Not available 1axc_B(100) 1axc_B/D/F (100), 2zvv_X/Y (100), 2zvw_I/J/K/L/M/N/O/P (100), 4rjf_B/D/F (100), More ... Phyre 8876165
P39099 Periplasmic pH-dependent serine endoprotease DegQ DegQ could degrade transiently denatured and unfolded proteins which accumulate More ... GO:0071575; C:integral component of external side of plasma membrane; ISA:EcoliW More ... Chaperone GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Escherichia coli 3stj_A(100) 3sti_A/B/C (100), 3stj_A/B/C/D/E/F/G/H/I/J/K/L (100), 4a8a_A/B/C/D/E/F/G/H/I/J/K More ... Phyre 22245966
P39633 Glutamate dehydrogenase EC:1.4.1.2 Devoted to catabolic function of glutamate (and other amino acids of the glutama More ... GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IDA:UniProtKB.
GO:0006520 More ... 		Transcription factor binding activity GO:0008150 biological_process
GO:0016070 RNA metabolic process
GO:0051252 regula More ... 		Bacillus subtilis 3k92_A(100) 3k92_A/B/C/D/E/F (100) Phyre 20630473
P39940 Enolase 2 Glycolysis GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
GO:0005934; C:cellula More ... 		Required for vacuole homotypic membrane fusion protein GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Saccharomyces cerevisiae 4bbn_A(70) 3olm_A (100), 4lcd_A/B (100), 5hpl_A/B (100) Phyre 16738406
P40429 60S ribosomal protein L13a Ribosome protein, part of 60S subunit of ribosome GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005829; C:cytosol; TAS:Reactome.
GO: More ... 		Translation inhibition Component of the GAIT complex (gamma interferon-activated More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Homo sapiens 4d5y_O(100) 4ug0_LO (100), 4v6x_CO (100), 5aj0_AO (100), 5lks_LO (100), 5t2c_I (100), 6ip5_2 More ... Phyre 14567916
P40926 Malate dehydrogenase, mitochondrial TCA cycle GO:0070062; C:extracellular exosome; IDA:UniProtKB.
GO:0005743; C:mitochondrial More ... 		RNA binding protein GO:0003674 molecular_function
GO:0005488 binding
GO:1901363 heterocyclic compo More ... 		Homo sapiens 2dfd_A(100) 2dfd_A/B/C/D (100), 4wle_A/B/C/D (100), 4wlf_A/B/C/D (100), 4wln_A/B/C/D (100), More ... Phyre 26520658
P41007 Bifunctional protein PyrR Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon More ... GO:0003723; F:RNA binding; IEA:UniProtKB-HAMAP.
GO:0004845; F:uracil phosphoribo More ... 		Binds mRNA transcriptional attenuation of the pyrimidine nucleotide biosynthetic More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Bacillus caldolyticus 2igb_A(100) 1non_A/B/C/D (100), 1xz8_A/B (100), 1xzn_A/B (100), 2igb_A/B (100) Phyre 9932459
P41182 Bcl6 B-cell lymphoma 6 protein isoform 1 Transcriptional repressor which is required for germinal center formation and an More ... GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005634; C:nucleus; IDA:UniProtKB.
G More ... 		Bcl6 can control the type of immune cell that develops in the bone marrow—playin More ... GO:0008150 biological_process
GO:0032502 developmental process
GO:0048869 cellul More ... 		Homo sapiens Microphthalmia, syndromic 2 (omim:300166) 3e4u_A(100) 1r28_A/B (100), 1r29_A (100), 1r2b_A/B (100), 2en2_A (100), 2eos_A (100), 2lce_A More ... Phyre 30516
P42227 STAT3 (Signal transducer and activator of transcription 3) Signaling protein and Transcription factor (STAT3 mediates the expression of a v More ... GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005829; C:cytosol; ISO:MGI.
GO:00057 More ... 		Electron transport chain GO:0009055;F:electron carrier activity
GO:0046872;F:metal ion binding;
GO:002290 More ... 		Mus musculus 1bg1_A(100) 1bg1_A (100), 3cwg_A/B (100), 4e68_A (100), 4zia_A/B/C/D/E (100) Phyre 19131594
P42383 60 kDa chaperonin Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ... 		Surface location controls bacterial growth - Stimulates monocyte cytokine synthe More ... GO:0045927; P:positive regulation of growth. Synonyms: up regulation of growth; More ... Helicobacter pylori 5da8_A(76) Phyre 9492175
P43067 Alcohol dehydrogenase 1 An alcohol + NAD+ = an aldehyde or ketone + NADH GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004022; F:alcohol dehydrogen More ... 		Plasminogen binding (humans plasminogen) GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Candida albicans 4w6z_A(74) Phyre 12622818
P43593 Ubiquitin carboxyl-terminal hydrolase 6 Deubiquitinase, enzyme associated with proteasome releases ubiquitin from ubiqui More ... GO:0000502; C:proteasome complex; IPI:SGD.
GO:0005838; C:proteasome regulatory p More ... 		Inhibits proteasome activity delays the degradation of ubiquitinated proteins by More ... GO:0044237 cellular metabolic process
GO:0048519 negative regulation of biologic More ... 		Saccharomyces cerevisiae 1vjv_A(100) 1vjv_A (100), 5a5b_8 (100), 5mpc_8 (100), 7qo4_8 (100), 7qo5_8 (100) Phyre 17018280
P43736 Chaperone protein DnaK Chaperone GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
GO:0006457; P:protein folding; I More ... 		Adhesion to host, unknow receptor. GO:0008150 biological_process
GO:0051704 multi-organism process
GO:0044419 inter More ... 		Haemophilus influenza 1dkg_D(79) Phyre 9125554
P44324 Aspartate ammonia-lyase L-aspartate = fumarate + NH3 GO:0005829; C:cytosol; IBA:GO_Central.
GO:0008797; F:aspartate ammonia-lyase act More ... 		Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Haemophilus influenzae Phyre 9092705
P45880 Voltage-dependent anion-selective channel protein 2 Ion channel GO:0070062; C:extracellular exosome; IDA:UniProtKB.
GO:0045121; C:membrane raft; More ... 		It also exhibits other extra-mitochondrial localizations as in
the plasma membra More ... 		GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellul More ... 		Homo sapiens Cancer PRLX 93936 4bum_X(83.5) Phyre 23355646
P46060 Ran GTPase-activating protein 1 GTPase activator for the nuclear Ras-related regulatory protein Ran, converting More ... GO:0016235; C:aggresome; IDA:HPA.
GO:1904115; C:axon cytoplasm; IEA:Ensembl.
GO: More ... 		At the kinetochore, CRM1 recruits the RanBP2-RanGAP1-SUMO complex that is requir More ... GO:0008150 biological_process
GO:0071840 cellular component organization or bi More ... 		Homo sapiens 2grr_B(100) 1z5s_C (100), 2grn_B (100), 2gro_B (100), 2grp_B (100), 2grq_B (100), 2grr_B (10 More ... Phyre 26793706
P46273 Phosphoglycerate kinase It converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate (glycolysis More ... GO:0097311; C:biofilm matrix; IDA:CGD.
GO:0009986; C:cell surface; IDA:CGD.
GO:0 More ... 		Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Candida albicans 2p9q_A(66) Phyre 22143554
P46398 60 kDa chaperonin Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ... 		Stimulation of bone resorption (in the pathology of localized juvenile periodont More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Aggregatibacter actinomycetemcomitans serotype c 4pkn_A(87) Phyre 7657790
P46531 Neurogenic locus notch homolog protein 1 Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 t More ... GO:0001669; C:acrosomal vesicle; IEA:Ensembl.
GO:0005912; C:adherens junction; I More ... 		Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 t More ... GO:0008150 biological_process
GO:0043170 macromolecule metabolic process
GO:0003 More ... 		Homo sapiens Breast neoplasm, Uterine cervical neoplasm, Congenital abdnormalities, Colonic n More ... Notch inhibitor, BMS-906024 2f8y_A(100) 1pb5_A (100), 1toz_A (100), 1yyh_A/B (100), 2f8x_K (100), 2f8y_A/B (100), 2he0_A More ... Phyre 20832754
P46777 Ribosomal Protein L5 Ribosomal protein, component of the large ribosomal subunit GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005829; C:cytosol; TAS:Reactome.
GO: More ... 		Inhibition of MDM2-mediated p53 ubiquitination and degradation GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens Diamond-Blackfan anemia 6 (omim:612561) 4d5y_D(100) 4ug0_LD (100), 4v6x_CD (100), 5aj0_AD (100), 5lks_LD (100), 5t2c_G (100), 6ip5_1 More ... Phyre 15308643
P46889 DNA translocase FtsK Essential cell division protein that coordinates cell division and chromosome se More ... GO:0005887; C:integral component of plasma membrane; IDA:EcoCyc.
GO:0016020; C:m More ... 		FtsK can remove proteins from DNA as it translocates, but translocation stops sp More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Escherichia coli 2j5p_A(100) 2ius_A/B/C/D/E/F (100), 2j5p_A (100), 5dcf_A (100) Phyre 22014899
P47543 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.18 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004365; F:glyceraldehyde-3-p More ... 		Mucin binding GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Mycoplasma genitalium 5m6d_A(61) 7jwk_A/B/C/D (100) Phyre 12787366
P47897 Glutamine--tRNA ligase Plays a critical role in brain development.
ATP + L-glutamine + tRNA(Gln) = AMP More ... 		GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005829; C:cytosol; IBA:GO_Central.
G More ... 		Interacts with ASK1 (Fas ligation activated apoptosis signal-regulating kinase 1 More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens Microcephaly, progressive, seizures, and cerebral and cerebellar atrophy (omim:6 More ... L-Glutamine 5bnz_A(64) 4r3z_C (100), 4ye6_A (100), 4ye8_A (100), 4ye9_A (100) Phyre 11096076
P47992 Chemokine lymphotactin Monomeric Ltn10 form activates the G protein-coupled receptor XCR1 on target leu More ... GO:0005623; C:cell; IEA:GOC.
GO:0005576; C:extracellular region; TAS:Reactome.
G More ... 		The Ltn40 form, which binds glycosaminoglycans, is dimeric and adoptds a previou More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ... 		Homo sapiens 1j8i_A(100) 1j8i_A (100), 1j9o_A (100), 2hdm_A (100), 2jp1_A/B (100), 2n54_A/B (100), 2nyz_D More ... Phyre 18364395
P48237 Ccm1p (Mitochondrial group I intron splicing factor CCM1) Supports bI4 maturase activity (removal of COB & COX1 fourth introns) GO:0005739; C:mitochondrion; IDA:SGD.
GO:0019843; F:rRNA binding; IDA:SGD.
GO:00 More ... 		Key to maintain the steady-state levels of the mitoribosome small subunit RNA (1 More ... GO:0008150 biological_process
GO:0065007 biological regulation
GO:0008152 metabo More ... 		Saccharomyces cerevisiae 8d8j_D (100), 8d8k_D (100) Phyre 22861139
P48376 5-demethoxyubiquinone hydroxylase, mitochondrial Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol ( More ... GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005739; C More ... 		Has also a structural role in the COQ enzyme complex, stabilizing other COQ poly More ... GO:0008150 biological_process
GO:0065007 biological regulation
GO:0050789 regula More ... 		Caenorhabditis elegans Phyre 26520802
P48570 Homocitrate synthase, cytosolic isozyme Acetyl-CoA + H2O + 2-oxoglutarate = (R)-2-hydroxybutane-1,2,4-tricarboxylate + C More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005634; C:nucleus; IDA:SGD.
More ... 		Influences repair at DNA double-stranded breaks. GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Saccharomyces cerevisiae 3ivs_A(79.8) Phyre 25628362
P49327 Fatty acid synthase Fatty acid synthetase catalyzes the formation of long-chain fatty acids from ace More ... GO:0005829; C:cytosol; IDA:HPA.
GO:0070062; C:extracellular exosome; IDA:UniProt More ... 		This multifunctional protein has 7 catalytic activities and an acyl carrier prot More ... GO:0003674 molecular_function
GO:0005488 binding
GO:1901363 heterocyclic compo More ... 		Homo sapiens <a href=""https://www.drugbank.ca/biodb/bio_entities/BE0000959"">Cerulenin
Orlis More ... 		1xkt_A(100) 1xkt_A/B (100), 2cg5_B (100), 2jfd_A/B/C/D (100), 2jfk_A/B/C/D (100), 2px6_A/B ( More ... Phyre 26520658
P49367 Homoaconitase, mithocondrial EC:4.2.1.36 Responsible for the dehydration of cis-homoaconitate to homoisocitric acid. GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulf More ... 		Mitochondrial DNA stability GO:0003674;F:molecular_function
GO:0005488;F: binding
GO:1901363;F: heterocyclic More ... 		Saccharomyces cerevisiae 4kp2_A(58) Phyre 15692048
P49577 Fructose-bisphosphate aldolase 2 D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate More ... GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC.
GO:0006 More ... 		Attaches actin filaments to TRAP proteins (transmembrane adhesive proteins of th More ... GO:0008150 biological_process
GO:0003674 molecular_function
GO:0005488 binding
G More ... 		Plasmodium berghei 4tr9_A(88) Phyre 17426153
P49610 Beta-N-acetylhexosaminidase Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-b More ... GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.
GO:0005576; C:extracellular regi More ... 		Deglycosylate complement components GO:0008150 biological_process
GO:0065007 biological regulation
GO:0002376 immune More ... 		Streptococcus pneumoniae 2YL8 2ltj_A (100), 2yl5_A/B/C/D (100), 2yl6_A (100), 2yl8_A (100), 2yl9_A/B/C/D (100) More ... Phyre 28265264
P49759 Dual specificity protein kinase CLK1 Dual specificity kinase acting on both serine/threonine and tyrosine-containing More ... GO:0005737; C:cytoplasm; IEA:Ensembl.
GO:0005634; C:nucleus; IEA:UniProtKB-SubCe More ... 		Acts to limit stress responses. Regulates the alternative splicing of tissue fac More ... GO:0008150 biological_process
GO:0065007 biological regulation
GO:0050789 regula More ... 		Homo sapiens ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxyla More ... 2exe_A(69) 1z57_A (100), 2vag_A (100), 5j1v_A/B/C (100), 5j1w_A/B/C (100), 5x8i_A/B (100), More ... Phyre 26520802
P49790 Nuclear pore complex protein Nup153 Component of the nuclear pore complex (NPC), a complex required for the traffick More ... GO:0005829; C:cytosol; IDA:HPA.
GO:0042405; C:nuclear inclusion body; IDA:UniPro More ... 		Involved in the quality control and retention of unspliced mRNAs in the nucleus; More ... GO:0003674 molecular_function
GO:0005198 structural molecule activity
GO:0017056 More ... 		Homo sapiens 2ebv_A(100) 2ebq_A (100), 2ebr_A (100), 2ebv_A (100), 2gqe_A (100), 4u0c_B (100), 4u0d_M/N/O More ... Phyre 26791761
P49792 E3 SUMO-protein ligase RanBP2 E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. GO:0005642; C:annulate lamellae; IDA:UniProtKB.
GO:0005813; C:centrosome; IBA:GO More ... 		Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via More ... GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment o More ... 		Homo sapiens Encephalopathy, acute, infection-induced, 3 (IIAE3) (omim:608033) 4i9y_A(100) 1rrp_B/D (100), 1xke_A (100), 1z5s_D (100), 2las_B (100), 3uin_D (100), 3uio_D ( More ... Phyre 26793706
P49841 Glycogen synthase kinase-3 beta AMP biosynthesis GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.
GO:0005813; C:cen More ... 		RNA binding and transcription factor regulation. GO:0003674 molecular_function
GO:0005488 binding
GO:1901363 heterocyclic compo More ... 		Homo sapiens Alzheimer disease 1j1b_A(100) 1gng_A/B (100), 1h8f_A/B (100), 1i09_A/B (100), 1j1b_A/B (100), 1j1c_A/B (100), More ... Phyre 26520658
P50142 Heat shock protein 60, mitochondrial May participate in assembly and/or disassembly of proteins imported into the mit More ... GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; I More ... 		Adhesin GO:0008150 biological_process
GO:0022610 biological adhesion 		Histoplasma capsulatum 4pj1_A(64) Phyre 22143554
P50570 Dynamin Membrane fission GO:0005813; C:centrosome; IEA:Ensembl.
GO:0045334; C:clathrin-coated endocytic v More ... 		1. Dynamic instability of microtubules in interphase; 2. Centrosome cohesion; 3. More ... GO:0008150; GO:0008150; P:biological_process. Synonyms: physiological process; b More ... Homo sapiens Lethal congenital contracture syndrome 5 (omim:615368) 4uud_A(86) 2ys1_A (100) Phyre 12498685
P50747 Biotin--protein ligase Post-translational modification of specific protein by attachment of biotin. Act More ... GO:0000785; C:chromatin; IDA:UniProtKB.
GO:0005737; C:cytoplasm; IDA:HPA.
GO:000 More ... 		Acts as a biotin-independent transcriptional repressor interacting with HDAC1, H More ... GO:0010468 regulation of gene expression
GO:1903506 regulation of nucleic acid-t More ... 		Homo sapiens Holocarboxylase synthetase deficiency (omim:253270) Biotin 3vtc.1.A Phyre 24239178
P51608 Methyl-CpG-binding protein 2 Chromosomal protein that binds to methylated DNA. It can bind specifically to a More ... GO:0005829; C:cytosol; IBA:GO_Central.
GO:0005615; C:extracellular space; IDA:Un More ... 		It also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct in More ... GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0 More ... 		Homo sapiens Angelman syndrome (omim:105830) 1ub1_A(97) 1qk9_A (100), 3c2i_A (100), 5bt2_A (100), 6c1y_A/B (100), 6ogj_A/B (100), 6ogk_A More ... Phyre 24636253
P52631 Signal transducer and activator of transcription 3 Signal transducer and transcription activator that mediates cellular responses t More ... GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005829; C:cytosol; TAS:Reactome.
GO: More ... 		Electron transport chain Rattus norvegicus 1bg1_A(100) Phyre 17379720
P52789 Hexokinase-2 Glycolysis GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IDA:UniP More ... 		RNA binding protein GO:0003674 molecular_function
GO:0005488 binding
GO:1901363 heterocyclic compo More ... 		Homo sapiens <a href=""https://www.drugbank.ca/biodb/bio_entities/BE0000780"">NADH
Citric Aci More ... 		2nzt_A(100) 2nzt_A/B (100), 5hex_A/B (100), 5hfu_A/B (100), 5hg1_A (100) Phyre 26520658
P52948 Nuclear pore complex protein Nup98-Nup96 Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup9 More ... GO:0005829; C:cytosol; TAS:Reactome.
GO:0043231; C:intracellular membrane-bounde More ... 		May anchor NUP153 and TPR to the NPC. GO:0003674 molecular_function
GO:0005198 structural molecule activity
GO:001705 More ... 		Homo sapiens Acute myeloid leukemia 1ko6_.(99) 1ko6_A/C (100), 2q5x_A (100), 2q5y_A/C (100), 3mmy_B/D/F/H (100), 4owr_B (100), More ... Phyre 26791761
P52987 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004365; F:glyceraldehyde-3-p More ... 		Binding to invertase, a mannoprotein of Saccharomyces GO:0003674 molecular_function
GO:0005488 binding
GO:0030246 carbohydrate binding More ... 		Lactococcus lactis 4qx6_A(78) Phyre 19898842