| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B3DSV2 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium longum | 4yws_A(66) | Phyre | 19574304 | |||||
| B5FRK2 | 60 kDa chaperonin | Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Adhesin | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Salmonella enterica subsp. enterica serovar Typhimurium str. 798 | ITasser | 17379720 | ||||||
| B7UI59 | Chaperone protein DnaK | Chaperone |
GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. GO:0006457; P:protein folding; I More ... |
Adhesion to Sulphogalacosylceramide. |
GO:0008150 biological_process GO:0003674 molecular_function GO:0005488 binding G More ... |
Escherichia coli O127:H6 | 1dkg_D(99) | Phyre | 16170762 | |||||
| B8DW74 | Phosphoglycerate mutase | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. | GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity More ... | Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium lactis | 1qhf_A(65) | Phyre | 17557824 | |||||
| B8GW64 | CTP synthase | Synthesizes CTP |
GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0003883; F:CTP synthase activity More ... |
Binds to CreS | Caulobacter crescentus | 1s1m_A(79) | Phyre | 22014899 | ||||||
| B8GXA0 | Localization factor PodJL | Directs pili assembly |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. GO:0007049; P:ce More ... |
Controls motility |
GO:0005515 protein binding molecular_function GO:0071973 bacterial-type flagellu More ... |
Caulobacter crescentus | 3uq3.1.A(10) | Phyre | 22014899 | |||||
| B8Q027 | Enolase | Glycolysis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
"Secreted Enolase has been suggested to suppress the immune response in insects" |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0050896 respo More ... |
Steinernema glaseri | 2akz_A(79) | Phyre | 22750626 | |||||
| B9DFG0 | P5CS (D1-Pyrroline-5 carboxylate synthetase) | Proline synthesis |
GO:0004349; F:glutamate 5-kinase activity; IEA:InterPro. GO:0004350; F:glutamate More ... |
Catalyzes committing steps from glutamate; tomato PRO1 with a polycistronic mess More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Arabidopsis thaliana | 2h5g_A(74) | Phyre | 9223347 | |||||
| B9DHK5 | Lysine-ketoglutarate reductase–saccharopine dehydrogenase (LKR–SDH) | Lysine catabolism (Lysine ketoglutarate reductase) |
GO:0006554; P:lysine catabolic process GO:0061759; F:alpha-ketoglutarate reducta More ... |
Saccharopine dehydrogenase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Arabidopsis thaliana | 1e5q_A(69) | Phyre | 12393892 | |||||
| B9DHQ2 | Mitochondrial processing peptidase (MPP alpha and beta subunits) | Mitochondrial protein import (cleavage of signal peptide) |
GO:0009507; C:chloroplast; IDA:TAIR. GO:0009570; C:chloroplast stroma; IEA:UniPr More ... |
Mitochondrial electrontransport proteins | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Arabidopsis, various species | Phyre | 10502092 | ||||||
| B9PW35 | Aldolase EC:4.1.2.13 | Splits the fructose 1,6-bisphosphate, into dihydroxyacetone phosphate & glyceral More ... |
GO:0090651; C:apical cytoplasm; IMP:CAFA. GO:0005615; C:extracellular space; IMP More ... |
It is essential for efficient host cell invasion | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Toxoplasma gondii | 4d2j_A(100) | Phyre | 19380114 | |||||
| C0L9R1 | bgl1D Beta-glucosidase | Beta-glucosidase |
GO:0008422;F: beta-glucosidase activity GO:0016983;F: Catalysis of the hydrolysi More ... |
Lipolytic activity (renamed Lip1C) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
uncultured microorganism | Phyre | 22116645 | ||||||
| C0S1J2 | Enolase EC: 4.2.1.11. | Glycolysis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Fibronectin binding |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Paracoccidioides brasiliensis | 1ebg_A(81) | Phyre | 19429745 | |||||
| C0S9Y0 | Malate synthase | Gklyoxylate cycle |
GO:0004474; F:malate synthase activity; IEA:UniProtKB-EC. GO:0006097; P:glyoxyla More ... |
Adhesion process (type I and IV collagen and fibronectin binding) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Paracoccidioides brasiliensis | 3cux_A(71.9) | Phyre | 25566229 | |||||
| C1G3G7 | Isocitrate lyase | Glyoxylate cycle |
GO:0004451; F:isocitrate lyase activity; IEA:InterPro. GO:0019752; P:carboxylic More ... |
Adhesion process (fibronectin and type IV collagen binding) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Paracoccidioides brasiliensis | 1dqu_A(85) | Phyre | 25566229 | |||||
| C1GLK1 | Aconitase | TCA cycle |
GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:E More ... |
Iron regulatory protein | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Paracoccidioides brasiliensis | 1aco_A(72) | Phyre | 25566229 | |||||
| C1GPZ3 | Fumarase | Catalyze the reversible hydratation of fumarate to malate. |
GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro. GO:0004333; More ... |
Adhesion to host | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Paracoccidioides brasiliensis | 1yfm_A(75) | Phyre | 25566229 | |||||
| C1KVC0 | DnaK | Acts as a chaperone. |
GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. GO:0006457; P:protein folding; I More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Listeria monocytogenes | 4f01_A(74) | Phyre | 15378750 | |||||
| C1KY94 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Listeria monocytogenes | 4a3r_A(82) | Phyre | 15378750 | |||||
| C1KZK6 | Elongation factor Tu | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Listeria monocytogenes | 1efc_A(80) | Phyre | 15378750 | |||||
| C2GUH0 | Glutamine synthetase | ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine. |
GO:0005737; C:cytoplasm; IEA:InterPro. GO:0005524; F:ATP binding; IEA:UniProtKB- More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium longum | 4s17_A(95) | Phyre | 20167618 | |||||
| C2GUH0 | Glutamine Synthetase | Glutamine Synthetase |
GO:0005737; C:cytoplasm; IEA:InterPro. GO:0005524; F:ATP binding; IEA:UniProtKB- More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium lactis | 4s17_A(95) | Phyre | 17557824 | |||||
| C3LDI0 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bacillus anthracis | 4a3r_A(80) | Phyre | 18456007 | |||||
| C4ME86 | 60 kDa chaperonin | Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... | GO:0005524; F:ATP binding; IEA:InterPro. | Stimulation of osteoclastogenesis - Stimulation of monocyte cytokine synthesis ( More ... |
GO:0008150;P:biological_process GO:0065007;P: biological regulation GO:0009987;P More ... |
Escherichia coli | 1gr5_A(100) | Phyre | 9718194 | |||||
| C6GGT7 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Fibronectin binding protein/adhesin |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus suis | 4ewj_A(100) | Phyre | 18757800 | |||||
| C6L8D6 | Chaperone protein DnaK | Chaperone |
GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. GO:0006457; P:protein folding; I More ... |
Adhesion to host, unknow receptor. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Bifidobacterium animalis | 1yuw_A(72) | Phyre | 20167618 | |||||
| C6S993 | Glyceraldehyde-3-phosphate dehydrogenase | Glycolysis |
GO:0051287; F:NAD binding; IEA:InterPro. GO:0050661; F:NADP binding; IEA:InterPr More ... |
Adhesion to host. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Neisseria meningitidis | 3cmc_O(71) | Phyre | 21062461 | |||||
| C6SIV9 | Aldolase EC:4.1.2.13 | Splits the fructose 1,6-bisphosphate, into dihydroxyacetone phosphate & glyceral More ... |
GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC. GO:0008 More ... |
It is a cell surface protein involved in cell adherence |
GO:0005488; F:binding. Synonyms: ligand. GO:0046812; F:host cell surface binding More ... |
Neisseria meningitidis | 5u4n_A(99) | Phyre | 20199602 | |||||
| C6SKU1 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Neisseria meningitidis | 4a3r_A(68) | Phyre | 17307854 | |||||
| C7C076 | ATP-dependent protease subunit HslV | Chaperone |
GO:0009376; C:HslUV protease complex; IEA:UniProtKB-HAMAP. GO:0005839; C:proteas More ... |
Adhesion to host, unknow receptor. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Helicobacter pylori | 1g3k_A(63) | Phyre | 1295059 | |||||
| C7GLI0 | Vhs3 - phosphopantothenoylcysteine decarboxylase subunit Vhs3 | Coenzyme A biosynthesis | GO:0003824; F:catalytic activity; IEA:InterPro. | Regulator of serine/threonine protein phosphatase | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 1e20_A(71) | Phyre | 19915539 | |||||
| C7GM32 | Gal1p | To phosphorilate galactose |
GO:0005737; C:cytoplasm; IEA:InterPro. GO:0005524; F:ATP binding; IEA:InterPro. More ... |
Gal1p activates Gal4p, the activator of GAL genes, by direct interaction with th More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 2aj4_A(99.8) | Phyre | 8658143 | |||||
| C7VDQ3 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005829; C:cytosol; ISS:UniProtKB. GO More ... |
Associated with epithelial cell binding |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Enterococcus faecalis | Phyre | 24362949 | ||||||
| C8UPL3 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0051287; F:NAD binding; IEA:InterPro. GO:0050661; F:NADP binding; IEA:InterPr More ... |
Bind plasminogen and fibrinogen - NAD-ribosylating activity. Binding to intestin More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Escherichia coli | 4qx6_A(71) | Phyre | 17449317 | |||||
| C8Z777 | Arg5,6 | Arginine biosynthesis |
GO:0005739; C:mitochondrion; IEA:InterPro. GO:0003991; F:acetylglutamate kinase More ... |
Transcriptional control (DNA binding transcription regulator) |
GO:0008150;P:biological_process GO:0065007;P: biological regulation GO:0008152;P More ... |
Saccharomyces cerevisiae | 3zzi_A(100) | Phyre | 15486299 | |||||
| C9WZY8 | Peroxiredoxin | Peroxiredoxin |
GO:0005623; C:cell; IEA:GOC. GO:0009055; F:electron carrier activity; IEA:InterP More ... |
Binding to plasminogen. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Neisseria meningitidis | Phyre | 17307854 | ||||||
| D0K1B1 | Peptidyl Prolyl cis,trans-Isomerase (PPI) EC:5.2.1.8 | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomeriza More ... |
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. GO More ... |
Induces apoptosis of gastric epithelial cells - Activates monocyte IL-6 synthesi More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Helicobacter pylori | 1clh_A(56) | Phyre | 15843568 | |||||
| D0VLV3 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
EgEno1 expression patterns in hydatid cyst components showed that these proteins More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Echinococcus granulosus | 2psn_A(77) | Phyre | 22750316 | |||||
| D2BRB9 | Pyruvate kinase EC:2.7.1.40 | Converts phosphoenolpyruvate (PEP) to pyruvate (glycolysis) |
GO:0016301; F:kinase activity; IEA:UniProtKB-KW. GO:0000287; F:magnesium ion bin More ... |
L. lactis cell surface protein that binds to yeast mannan |
GO:0003674 molecular_function GO:0005488 binding GO:0030246 carbohydrate binding More ... |
Lactococcus lactis subsp. lactis | 2e28_A(63) | Phyre | 19898842 | |||||
| D3R5K8 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium animalis subsp. lactis | 4a3r_A(61) | Phyre | 20167618 | |||||
| D3R759 | HtrA | Serine protease |
GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. GO:0006457; P:protein folding; I More ... |
Involved in nasopharyngeal colonization | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus pneumoniae | 4rtf_D(75) | Phyre | 19721085 | |||||
| D5GYN9 | Glutamine Synthetase | Synthesis of Glutamine |
GO:0005737; C:cytoplasm; IEA:InterPro. GO:0005524; F:ATP binding; IEA:UniProtKB- More ... |
Binding to plasmin(ogen); Binding to collagen I and laminin & Binding to other b More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Lactobacillus crispatus | 4lnf_A(61) | Phyre | 22389474 | |||||
| D5H2B9 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0051287; F:NAD binding; IEA:InterPro. GO:0050661; F:NADP binding; IEA:InterPr More ... |
Binding to Plasminogen |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Lactobacillus crispatus | 5m6d_A(67) | Phyre | 24833341 | |||||
| D5H2G7 | Phosphoglucose isomerase (Glucose-6-phosphate isomerase) EC:5.3.1.9 | Catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate (glyco More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004347; F:glucose-6-phosphat More ... |
Adhesive enzyme onto bacterial surface |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Lactobacillus crispatus | 3ifs_A(72) | Phyre | 22389474 | |||||
| D6S5V6 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Inhibitor of Neisseria binding. Plasminogen and laminin binding. Binding to lami More ... |
GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Lactobacillus johnsonii | 4mks_A(90) | Phyre | 20385752 | |||||
| D9IL10 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... | GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) More ... | Responsible for a complement factor C3 binding activity |
GO:0001848 (complement binding) GO:0045916(negative regulation of complement act More ... |
Haemonchus contortus | 1u8f_O(87) | Phyre | 23927077 | |||||
| E0PZW1 | Phosphoglycerate mutase | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate | GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity More ... | Plasminogen binding protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus sp. oral | 1bq3_A(62) | Phyre | 18310038 | |||||
| E3ER63 | Phosphoglycerate mutase | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. | GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity More ... | Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium bifidum | 1rii_A(69) | Phyre | 17557824 | |||||
| E6J203 | Triosephosphate isomerase | D-glyceraldehyde 3-phosphate = glycerone phosphate. |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004807; F:triose-phosphate i More ... |
Plasminogen binding. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus anginosus | 2btm_A(58) | Phyre | 18310038 | |||||
| E6KIJ3 | Phosphoglycerate kinase EC:2.7.2.3 | It converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate (glycolysis More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Binding to plasminogen |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus oralis ATCC 49296 | 3zlb_A(96) | Phyre | 18310038 | |||||