| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A059U5R2 | 60S ribosomal protein L44 | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0003735; F:structural constituent o More ... |
It supports abiotic stress resistance |
GO:0008150 biological_process GO:0050896 response to stimulus GO:0009628 respons More ... |
Aspergillus glaucus | 3j6x_82(83) | Phyre | 24814782 | |||||
| A0A0H2Q1X0 | Glutamine synthetase | ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine. |
GO:0015930; F:glutamate synthase activity; IEA:InterPro. GO:0006537; P:glutamate More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium bifidum | 1ea0_A(64) | Phyre | 20167618 | |||||
| A0A0H3CDS3 | Bifunctional regulator KidO | Activates DivJ |
GO" id="GO:0016021"C:integral component of membrane GO:0005622;C:intracellular G More ... |
Binds to FtsZ | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Caulobacter crescentus | Phyre | 22014899 | ||||||
| A0A0K1MVR4 | Class A sortase | Integral component of membrane. | GO:0016021;C:integral component of membrane | Inhibit the internalization of S. aureus, a major etiologic agent of mastitis, i More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Lactobacillus casei | Phyre | 28323870 | ||||||
| A0A0S4TK55 | Importin-beta2 | Govern selective transport of proteins into the nucleus |
GO:0008565; F:protein transporter activity; IEA:InterPro. GO:0006886; P:intracel More ... |
It also selectively targets the motor protein Kif17 to primary cilia | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Cryptosporidium hominis | 2bku_B(74) | Phyre | 20526327 | |||||
| A0A1F1EC06 | Enolase EC: 4.2.1.11. | Glycolysis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Oral streptococci | Phyre | 18310038 | ||||||
| A0A1S1FAM2 | Phosphoglycerate kinase | ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus anginosus | Phyre | 21729749 | ||||||
| A0KGD3 | Phosphoglycerate kinase EC:2.7.2.3 | It converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate (glycolysis More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Cell surface virulence factor. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Aeromonas hydrophila subsp. hydrophila | 1zmr_A(79) | Phyre | 22143554 | |||||
| A0QQU5 | 60 kDa chaperonin 1 | Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Essential for biofilm formation | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Mycobacterium smegmatis | 3rtk_A(95) | Phyre | 16325580 | |||||
| A1A528 | ZW10 (Centromere/kinetochore protein zw10 homolog) | Trafficking between the ER and Golgi |
GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell. GO:000573 More ... |
Kinetochore component, termination of the spindle checkpoint | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Osteosarcoma | 7qpg_W/X (100) | Phyre | 15029241 | ||||
| A1AGC3 | S9 | Ribosomal protein |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0022627; C:cytosolic small ribosomal subun More ... |
DNA repair |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Escherichia coli | 1p6g_I(100) | Phyre | 2552436 | |||||
| A1AGJ5 | S8 | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0019843; F:rRNA binding; IEA:UniPro More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Escherichia coli | 1p6g_H(100) | Phyre | 6206783 | |||||
| A1AIF7 | L10 | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0070180; F:large ribosomal subunit More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Escherichia coli | 3j0t_J(100) | Phyre | 6206783 | |||||
| A1KFR2 | 60 kDa chaperonin | Chaperone | GO:0005524; F:ATP binding; IEA:InterPro. | Adhesin to CD43 on macrophage surface |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Mycobacterium tuberculosis | 3rtk_B(100) | Phyre | 19470749 | |||||
| A1KFR2 | 60 kDa chaperonin 1 | Chaperone |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular regi More ... |
Adhesion to DC-SIGN |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Mycobacterium bovis BCG | 3rtk_B(100) | Phyre | 21203928 | |||||
| A1L4U4 | GTP-cyclohydrolase-II–3,4-dihydroxy-2-butanone-4-phosphate synthase (GTP2–DHBP) | Riboflavinsynthesis | GO:0008686; F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity; IEA:InterP More ... | Fusion might be a kinetic solution for balancing substrate input from convergent More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0045036 protei More ... |
Arabidopsis thaliana | 4i14_A(71) | Phyre | 10783978 | |||||
| A2DHT2 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... | GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) More ... | Binds fibronectin and plasminogen and collagen. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Trichomonas vaginalis | 3gnq_A(60) | Phyre | 17379720 | |||||
| A4IWC5 | 60 kDa chaperonin | Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:I More ... |
More active monocyte activator than LPS and synergizes with LPS | GO:0008150; P:biological_process. GO:0052173; P:response to defenses of other or More ... | Francisella tularensis subsp. tularensis | 1aon_O(67) | Phyre | 20123721 | |||||
| A4W2T1 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Binding to intestinal epithelial cells | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus suis | 4ewj_A(100) | Phyre | 19848587 | |||||
| A6QQT4 | Aldehyde dehydrogenase | Alcohol metabolism |
GO:0005783; C:endoplasmic reticulum; IEA:Ensembl. GO:0070062; C:extracellular ex More ... |
Lens protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005198; F:st More ... |
Bos taurus | 4qgk_A(86) | Phyre | 22143554 | |||||
| A6R3K7 | PPI (Peptidyl Prolyl cis,trans-Isomerase (PPI) EC:5.2.1.8) | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomeriza More ... |
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. GO More ... |
Binding to VLA5 |
GO:0008150 biological_process GO:0003674 molecular_function GO:0005488 binding G More ... |
Histoplasma capsulatum | 1h0p_A(73) | Phyre | 18981131 | |||||
| A6ZSN7 | S20 | Ribosomal protein |
GO:0015935; C:small ribosomal subunit; IEA:InterPro. GO:0003723; F:RNA binding; More ... |
Transcription |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Yeast (Saccharomyces cerevisiae) | 3j6x_20(100) | Phyre | 8021936 | |||||
| A6ZUW4 | L30 | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0003735; F:structural constituent o More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Yeast (Saccharomyces cerevisiae) | 1t0k_B(100) | Phyre | 8299940 | |||||
| A6ZZQ6 | Aldolase EC:4.1.2.13 | Splits the fructose 1,6-bisphosphate, into dihydroxyacetone phosphate & glyceral More ... |
GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:InterPro. GO:0008270; More ... |
V-ATPase assembly (ALD associates with and supports proper functioning of the va More ... |
GO:0003674;F:molecular_function GO:0005488;F: binding GO:0005515;F: protein bind More ... |
Saccharomyces cerevisiae | 1b57_A(66) | Phyre | 17576770 | |||||
| A7KT66 | Ancillary pilus subunit | Integral component of membrane. |
GO:0005575;cellular_component GO:0016020 membrane GO:0044425 membrane part GO:00 More ... |
Promote adhesion to and invasion of macrophages |
GO:0008150 biological_process GO:0065007 biological regulation GO:0002376 immune More ... |
Streptococcus pneumoniae | Phyre | 28265264 | ||||||
| A7L763 | Tuf (Translation elongation factor Tu) | Translation elongation factor (proteins used in protein synthesis in the cell) |
GO:0005525; F:GTP binding; IEA:InterPro. GO:0003746; F:translation elongation fa More ... |
Factor H (Binding to plasma Factor H and Factor H-related protein 1 (FHR-1)) and More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Pseudomonas aeruginosa | 4zv4_A(100) | Phyre | 17709513 | |||||
| A7LKP5 | Glucose-6-phosphate isomerase | Catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate (glyco More ... |
GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC. GO:00060 More ... |
In the vesicle fluid seems to be related to cellular proliferation and/or differ More ... |
GO:0008150 biological_process GO:0035821 modification of morphology or physiolo More ... |
Echinococcus multilocularis | 2cvp_A(72) | Phyre | 20600070 | |||||
| A7UKY0 | MDM2 (E3 ubiquitin-protein ligase Mdm2) | Down-regulation of p21 |
GO:0005730; C:nucleolus; IDA:UniProtKB. GO:0043066; P:negative regulation of apo More ... |
Activation of estrogen receptor alpha |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0060089; F:mo More ... |
Homo sapiens | Glioma, susceptibility (omim:137800) | 2lzg_A(100) | Phyre | 14761977 | ||||
| A7VMH8 | AtlA (autolysin) | Autolysin |
GO:0003796; F:lysozyme activity; IEA:UniProtKB-EC. GO:0005975; P:carbohydrate me More ... |
is a fibronectin-binding protein and contributes to bacterial survival in the bl More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus mutans | Phyre | 19818020 | ||||||
| A7ZUJ7 | L1 | Ribosomal protein |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0022627; C:cytosolic small ribosomal subun More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Escherichia coli | 2gya | Phyre | 6206783 | |||||
| A8AUR6 | Elongation factor G | Catalyzes the GTP-dependent ribosomal translocation step during translation elon More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Adhsein, binds to salivary Mucin MUC7 | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus gordonii | 2bv3_A(78) | Phyre | 19671172 | |||||
| A8AVC1 | Protein translocase subunit SecA | Part of the Sec protein translocase complex. Interacts with the SecYEG preprotei More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; I More ... |
Binding to salivary mucin |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus gordonii | 1tf5_A(68) | Phyre | 19671172 | |||||
| A8AWA0 | Elongation factor Tu | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Binding to salivary mucin |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus gordonii | 1efc_A(82) | Phyre | 19671172 | |||||
| A8AWF1 | Putative pyruvate, phosphate dikinase regulatory protein | Bifunctional serine/threonine kinase and phosphorylase involved in the regulatio More ... |
GO:0043531; F:ADP binding; IEA:UniProtKB-HAMAP. GO:0005524; F:ATP binding; IEA:I More ... |
Binding to salivary mucin |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus gordonii | 5d0n_A(60.8) | Phyre | 19671172 | |||||
| A8AY46 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Binding to salivary mucin MUC7 |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus gordonii | 1w6t_A(97) | Phyre | 19671172 | |||||
| A8AZI3 | DNA-directed RNA polymerase subunit beta | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using t More ... |
GO:0003677; F:DNA binding; IEA:UniProtKB-HAMAP. GO:0003899; F:DNA-directed RNA p More ... |
Binding to salivary mucin |
GO:0003674 molecular_function GO:0005488 binding GO:0050840 extracellular matrix More ... |
Streptococcus gordonii | 4g7h_C(62) | Phyre | 19671172 | |||||
| A8VHK4 | Enolase (Alpha-enolase) EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycoplasma fermentans | 4a3r_A(62) | Phyre | 17938226 | |||||
| A9M296 | Chaperone protein DnaK | Acts as a chaperone. |
GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. GO:0006457; P:protein folding; I More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Neisseria meningitidis | 1dkg_D(77) | Phyre | 17307854 | |||||
| A9M4E5 | Peroxiredoxin 2 family protein/glutaredoxin | Cell redox homeostasis. |
GO:0005623; C:cell; IEA:GOC. GO:0009055; F:electron carrier activity; IEA:InterP More ... |
Plasminogen binding. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Neisseria meningitidis | 1nm3_A(76) | Phyre | 17379720 | |||||
| A9SVI7 | Presenilin EC:2.7.1.1 | Presenilin enhancer-2 subunit of gamma secretase |
GO:0070765; C:gamma-secretase complex; IBA:GO_Central. GO:0005798; C:Golgi-assoc More ... |
Cytoskeletal function | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Physcomitrella patens | Phyre | 17684101 | ||||||
| B1A031 | Superoxide dismutase EC:1.15.1.1 | Destroys radicals which are normally produced within the cells and which are tox More ... |
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004784; F:superoxide dism More ... |
Adhesin binding mucus-associated proteins. Binding to epithelial cell ldolase, G More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium avium subsp. avium | 1gn3_A(83) | Phyre | 15207805 | |||||
| B1LHD3 | L4 | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0019843; F:rRNA binding; IEA:UniPro More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Escherichia coli | 2j28_E(100) | Phyre | 1764518 | |||||
| B1N649 | CbpA | Surface proteins noncovalently bound to the phosphorylcholine moiety of the cell More ... |
GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0016020; C:membran More ... |
Virulence (colonization of the nasopharynx) | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus pneumoniae | 2pms_C(84.3) | Phyre | 10992472 | |||||
| B1Y9D1 | tRNA-splicing endonuclease | Endonuclease that removes tRNA introns. |
GO:0016829; F:lyase activity; IEA:UniProtKB-KW. GO:0000213; F:tRNA-intron endonu More ... |
Generate circular SRP RNA molecules that can bind to SRP19 and SRP54. The circul More ... |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compoun More ... |
Pyrobaculum neutrophilum | Phyre | 26499493 | ||||||
| B1YAL1 | Fructose-1,6-bisphosphate aldolase/phosphatase | Fructose-1,6-bisphosphatase, enzyme dephosphorylation of FBP to fructose-6-phosp More ... | GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-EC More ... | Fructose-1,6-bisphosphate aldolase, enzyme reversible aldol condensation of dihy More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Thermoproteus neutrophilus | 3t2c_A(100) | 3t2b_A (100), 3t2c_A (100), 3t2d_A (100), 3t2e_A (100), 3t2f_A (100), 3t2g_A (10 More ... | Phyre | 21983965 | ||||
| B2ILT3 | Choline binding protein G | Surface proteins noncovalently bound to the phosphorylcholine moiety of the cell More ... | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | Virulence (colonization of the nasopharynx) | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus pneumoniae | 2v04_A(81.8) | Phyre | 10992472 | |||||
| B2INL9 | Choline binding protein D | Surface proteins noncovalently bound to the phosphorylcholine moiety of the cell More ... | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | Virulence (colonization of the nasopharynx) | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Streptococcus pneumoniae | 2v04_A(80.4) | Phyre | 10992472 | |||||
| B2IR92 | LytC (Lysozyme) | Lisozyme |
GO:0003796; F:lysozyme activity; IEA:InterPro. GO:0005975; P:carbohydrate metabo More ... |
Biofilm matrices are responsible for the cohesion and three-dimensional architec More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus pneumoniae | 2ww5_A(100) | Phyre | 22913814 | |||||
| B2LXU3 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... | GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) More ... | Binding to plasminogen. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Schistosoma bovis | 1gpd_G(76) | Phyre | 16962583 | |||||
| B2SJM1 | Phosphoglucose isomerase EC:5.3.1.9 | Catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate (glyco More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004347; F:glucose-6-phosphat More ... |
Involved in virulence (mechanism of action has not yet been identified) | GO:0051704; P:multi-organism process. Synonyms: interaction between organisms; p More ... | Xanthomonas oryzae pv. oryzae | 2o2c_A(57) | Phyre | 18943766 | |||||