| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P23219 | Cyclooxygenase-1 EC:1.14.99.1 | Prostaglandin G/H synthase 1 |
GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005789; C:endoplasmic reticulum memb More ... |
Heme-dependent peroxidase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Homo sapiens | BLEEDING DISORDER, PLATELET-TYPE, 12 (omim:605735) | Acetaminophen, Aspirin, Diclofenac, Fenoprofen, Flurbiprofen, Fosfosal, Icosapen More ... | 2oye_P(92) | 6y3c_A (100) | Phyre | 8121489 | ||
| P23256 | Protein MalY | Beta-cystathionase, enzyme cleavage of cystathionine to homocysteine, ammonia, a More ... |
GO:0004121; F:cystathionine beta-lyase activity; IDA:EcoCyc. GO:0080146; F:L-cys More ... |
Transcription regulation binds to MalT activator of mal regulon and prevents its More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Escherichia coli | 1d2f_A(100) | 1d2f_A/B (100), 8bob_A/B (100) | Phyre | 11867639 | ||||
| P23381 | Tryptophan--tRNA ligase, cytoplasmic | Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS la More ... |
GO:0005737; C:cytoplasm; TAS:UniProtKB. GO:0005829; C:cytosol; TAS:Reactome. GO: More ... |
Forms complex with the catalytic subunit of DNA-dependent protein kinase (DNA-PK More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | 1r6t_A(99) | 1o5t_A (100), 1r6t_A/B (100), 1r6u_A/B (100), 1ulh_A/B (100), 2ake_A (100), 2azx More ... | Phyre | 22504299 | ||||
| P23396 | S3 | Ribosomal protein |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; IDA:UniProtKB. GO More ... |
DNA repair |
GO:0003674 molecular_function GO:0003824 catalytic activity GO:0016788 hydrolase More ... |
Homo sapiens | Colon adenocarcinomas (omim:600454) | 3j7p_SD(100) | 1wh9_A (100), 4ug0_SD (100), 4v6x_AD (100), 5a2q_D (100), 5aj0_BD (100), 5flx_D More ... | Phyre | 7775413 | |||
| P23568 | Elongation factor Tu | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Binding to fibronectin |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycoplasma pneumoniae | 3u2q_A(76) | 7paj_9 (100), 7pak_9 (100), 7pha_9 (100), 7pi9_9 (100), 7pip_9 (100) | Phyre | 12421310 | ||||
| P24058 | Delta crystallin II EC:4.3.2.1 | Lens crystallin |
GO:0004056; F:argininosuccinate lyase activity; IDA:UniProtKB. GO:0005212; F:str More ... |
Argininosuccinate lyase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Anas platyrhynchos | 1hy1_A(100) | 1auw_A/B/C/D (100), 1dcn_A/B/C/D (100), 1hy1_A/B/C/D (100), 1k7w_A/B/C/D (100), More ... | Phyre | 2462567 | ||||
| P24228 | D-alanyl-D-alanine carboxypeptidase DacB | Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase More ... |
GO:0030288; C:outer membrane-bounded periplasmic space; IMP:EcoliWiki. GO:000418 More ... |
Endopeptidase, enzyme |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Escherichia coli | 2ex2_A(100) | 2ex2_A (100), 2ex6_A (100), 2ex8_A (100), 2ex9_A (100), 2exa_A (100), 2exb_A (10 More ... | Phyre | 16411754 | ||||
| P24494 | S19 (40S ribosomal protein S19G) | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0003735; F:structural constituent o More ... |
Regulation of development (required for chromatin condensation) |
GO:0008150 biological_process GO:0050793 regulation of developmental process More ... |
Ascaris lumbricoides | 3j7p_ST(58) | Phyre | 8052853 | |||||
| P24500 | Flagellar basal body rod protein FlgB | Structural component of flagellum, the bacterial motility apparatus. Part of the More ... |
GO:0030694; C:bacterial-type flagellum basal body, rod; IEA:InterPro. GO:0009424 More ... |
Extra-chromosomal DNA maintenance |
GO:0008150 biological_process GO:0009987 cellular process GO:0044763 single-orga More ... |
Bacillus subtilis | Phyre | 25843804 | ||||||
| P26623 | PPI (Peptidyl Prolyl cis,trans-Isomerase (PPI) EC:5.2.1.8) | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomeriza More ... |
GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell. GO:0003755; F:peptidyl More ... |
Is implicated in initiation of chlamydial infection. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Chlamydia trachomatis | Phyre | 7682281 | ||||||
| P27278 | Trifunctional NAD biosynthesis/regulator protein NadR | Nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (R More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; I More ... |
Transcriptional repressor binds to the nadB operator DNA sequence Increasing NAD More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Escherichia coli | 1lw7_A(70) | 8x7f_A/D/G/J (100) | Phyre | 10464228 | ||||
| P27302 | Transketolase 1 | Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose More ... |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0030145; F:manganese ion binding; IDA:EcoC More ... |
Transcriptional regulator |
GO:0016021;C:integral component of membrane GO:0005886;C:plasma membrane GO:0006 More ... |
Escherichia coli | 2r8o_A(100) | 1qgd_A/B (100), 2r5n_A/B (100), 2r8o_A/B (100), 2r8p_A/B (100), 5hht_A/B (100), More ... | Phyre | 17850260 | ||||
| P27487 | CD26/DPPIV | Cell surface glycoprotein receptor involved in the costimulatory signal essentia More ... |
GO:0016324; C:apical plasma membrane; IDA:UniProtKB. GO:0009986; C:cell surface; More ... |
The protein functions as (1) serine protease, (2) receptor, (3) costimulatory pr More ... |
GO:0003674 molecular_function GO:0060089 molecular transducer activity GO:000487 More ... |
Homo sapiens | <a href="http://www.drugbank.ca/biodb/bio_entities/BE0000854"target=_blank">Saxa More ... | 2qt9_A(100) | 1j2e_A/B (100), 1n1m_A/B (100), 1nu6_A/B (100), 1nu8_A/B (100), 1pfq_A/B (100), More ... | Phyre | 12647932 | |||
| P27635 | L10 ribosomal protein | Component of the 60S ribosomal subunit |
GO:0005829; C:cytosol; TAS:Reactome. GO:0022625; C:cytosolic large ribosomal sub More ... |
Negative regulator of c-Jun in transcription | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | utism, susceptibility to, X-linked 5 (omim:300847) | 2pa2_A(100) | 2pa2_A/B (100), 5aj0_AI (100), 6ole_K (100), 6olf_K (100), 6olg_AI (100), 6oli_K More ... | Phyre | 10508860 | |||
| P27797 | Calreticulin | Intracellular function: A chaperone (glycoprotein folding and Ca2+ homeostasis) More ... |
GO:0001669; C:acrosomal vesicle; IEA:Ensembl. GO:0009986; C:cell surface; TAS:BH More ... |
Extracellular function (non-classical secretion routes): Cell adhesion and migra More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0060089; F:mo More ... |
Homo sapiens | Cardiomyopathy, familial hypertrophic, 19 (omim:613875) | Antihemophilic Factor, Tenecteplase, Melatonin, lanoteplase | 3rg0_A(95) | 2clr_C/F (100), 3dow_B (100), 3pos_A/B/C (100), 3pow_A (100), 5lk5_A/B/C/D/E/F/G More ... | Phyre | 11306273 | ||
| P27958 | Genome polyprotein | Core protein packages viral RNA to form a viral nucleocapsid, and promotes virio More ... |
GO:0039714; C:cytoplasmic viral factory; IDA:UniProtKB. GO:0033116; C:endoplasmi More ... |
Also regulates many host cellular functions such as signaling pathways and apopt More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0009987 cellul More ... |
Hepatitis C virus | 3hkw_A(97) | 1a1r_A/B (100), 1a1v_A (100), 1cwx_A (100), 1hei_A/B (100), 1jr6_A (100), 1n1l_A More ... | Phyre | 26445449 | ||||
| P28241 | Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial | Performs an essential role in the oxidative function of the citric acid cycle. |
GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD. GO More ... |
Binds mRNA binds specifically to 5'-untranslated leaders of mitochondrial mRNAs |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Saccharomyces cerevisiae | 3blx_B(100) | 3blv_B/D/F/H (100), 3blw_B/D/F/H/J/L/N/P (100), 3blx_B/D/F/H/J/L/N/P (100) | Phyre | 7505425 | ||||
| P28482 | ERK2 (signal-regulated kinases) EC:2.7.11.24 | Mitogen-activated protein kinase 1 (MAP kinase) |
GO:0030424; C:axon; IEA:Ensembl. GO:0035578; C:azurophil granule lumen; TAS:Reac More ... |
Transcriptional repressor | O:0008150; P:biological_process. Synonyms: physiological process; biological pro More ... | Homo sapiens | Truncus arteriosus (omim:217095) | LLZ16407, PD184352, PD98059, Ro092210, U0126 | 1tvo_A(100) | 1pme_A (100), 1tvo_A (100), 1wzy_A (100), 2ojg_A (100), 2oji_A (100), 2ojj_A (10 More ... | Phyre | 19879846 | ||
| P28834 | Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial | Performs an essential role in the oxidative function of the citric acid cycle. A More ... |
GO:0005829; C:cytosol; TAS:Reactome. GO:0005758; C:mitochondrial intermembrane s More ... |
Binds mRNA binds specifically to 5'-untranslated leaders of mitochondrial mRNAs |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Saccharomyces cerevisiae | 3blx_A(100) | 3blv_A/C/E/G (100), 3blw_A/C/E/G/I/K/M/O (100), 3blx_A/C/E/G/I/K/M/O (100) | Phyre | 7505425 | ||||
| P29453 | L4 | Ribosomal protein |
GO:0022625; C:cytosolic large ribosomal subunit; IDA:SGD. GO:0003723; F:RNA bind More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Yeast (Saccharomyces cerevisiae) | 3j6x_L8(97) | Phyre | 2065661 | |||||
| P29474 | Endothelial Nitric Oxide Synthase EC:1.14.13.39 | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxat More ... |
GO:0005901; C:caveola; IDA:BHF-UCL. GO:0005737; C:cytoplasm; IDA:BHF-UCL. GO:000 More ... |
Synthesis of sulfate from sulfane or sulfide sulfur and superoxide. Bounding to More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Alzheimer disease (omim:104300) | L-NMMA, L-NAME, ACCLAIM | 4d1o_A(100) | 1m9j_A/B (100), 1m9k_A/B (100), 1m9m_A/B (100), 1m9q_A/B (100), 1m9r_A/B (100), More ... | Phyre | 2492 | ||
| P30041 | Peroxiredoxin-6 EC:1.11.1.15 | 1-Cys Peroxiredoxin (peroxidase) |
GO:0005913; C:cell-cell adherens junction; IDA:BHF-UCL. GO:0005737; C:cytoplasm; More ... |
Phospholipase aiPLA2 |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Homo sapiens | Lung cancer, Hepatocellular carcinoma, Myocardial Ischemia, Dermatitis | 5b6m_A(100) | 1prx_A/B (100), 5b6m_A/B/C/D/E/F (100), 5b6n_A/B/C/D/E/F (100) | Phyre | 10893423 | |||
| P30575 | Enolase | Glycolysis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Candida albicans | 2one.1.A(78) | 7v67_A/B/C/D (100), 7vrd_A/B/C/D (100) | Phyre | 12867553 | ||||
| P30749 | Molybdopterin synthase catalytic subunit | Converts molybdopterin precursor Z to molybdopterin. This requires the incorpora More ... |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0030366; F:molybdopterin synthase acti More ... |
Interaction with MBIP |
GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL. GO:00 More ... |
Escherichia coli | 1fm0_E(100) | 1fm0_E (100), 1fma_E (100), 1nvi_E (100), 1nvj_A/B/C/D/E/F (100), 3bii_E (100) | Phyre | 28284029 | ||||
| P31009 | S2 (40S ribosomal protein S2) | Ribosomal protein |
GO:0005737; C:cytoplasm; IDA:FlyBase. GO:0022626; C:cytosolic ribosome; IDA:FlyB More ... |
Regulation of development (plays a role in oogenesis and is necessary for matura More ... |
GO:0008150 biological_process GO:0050793 regulation of developmental process More ... |
Drosophila melanogaster | 4v6w_AC(100) | 4v6w_AC (100), 6xu6_AC (100), 6xu7_AC (100), 6xu8_AC (100) | Phyre | 7982558 | ||||
| P31230 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 | Scaffold protein in the multisynthase complex forms a multi-protein complex with More ... |
GO:0017101; C:aminoacyl-tRNA synthetase multienzyme complex; ISS:HGNC. GO:000998 More ... |
Cytokine roles in angiogenesis - inducing endothelial cell migration induces mat More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Mus musculus | 1fl0_A(94) | Phyre | 20306515 | |||||
| P31294 | 60 kDa chaperonin | Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Adhesion to glycosphinngolipids. Adhesin. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Haemophilus ducreyi | 2eu1_A(88) | Phyre | 22143554 | |||||
| P31306 | Oligopeptide-binding protein SarA | May be involved in the expression of cell surface properties important for colon More ... |
GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0015833; P:peptide tran More ... |
Binding to salivary mucin |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus gordonii | Phyre | 19671172 | ||||||
| P31681 | 60 kDa chaperonin | Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Activates monocyte cytokine synthesis - Oxidation of LDL - Stimulation of vascul More ... |
GO:0008150;P:biological_process GO:0065007;P: biological regulation GO:0002376;P More ... |
Chlamydia pneumoniae (Chlamydophila pneumoniae) | 2eu1_A(67) | Phyre | 9711934 | |||||
| P32189 | Glycerol Kinase EC:2.7.1.30 | It converts glycerol to sn-glycerol 3-phosphate (glycolysis) |
GO:0005829; C:cytosol; TAS:Reactome. GO:0070062; C:extracellular exosome; IDA:Un More ... |
ATP-stimulated translocation protein (ASTP), porin binding, apoptosis, lysosome More ... |
GO:0009987 cellular process GO:0044699 single-organism process GO:0050789 regula More ... |
Homo sapiens | Glycerol kinase deficiency (omim:307030) | 2d4w_A(61) | Phyre | 8884278 | ||||
| P32527 | Zuo1 Ribosome-associated chaperone zuotin | Co-Chaperone of the Hsp70, Ssb, that facilitates the folding of nascent polypept More ... |
GO:0005737; C:cytoplasm; IDA:SGD. GO:0005730; C:nucleolus; IMP:SGD. GO:0005844; More ... |
It has the ability to directly interact with and activate the transcription fact More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0044877 macromolecular compl More ... |
Saccharomyces cerevisiae | 5dje_A(99) | 2lwx_A (100), 5dje_A/B (100), 7x34_C (100), 7x3k_A (100) | Phyre | 23084974 | ||||
| P32856 | Epimorphin, syntaxin | Morphogen signaling (essential for epithelial morphogenesis) |
GO:0016323; C:basolateral plasma membrane; IDA:HGNC. GO:0070062; C:extracellular More ... |
Stimulates cell adhesion and/or motility upon export, facilitating specific step More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | 3c98_B(69) | Phyre | 17535848 | |||||
| P33095 | S15a (40S ribosomal protein S15a) | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0003735; F:structural constituent o More ... |
Regulation of development (mRNA for S15a is upregulated during oogenesis) |
GO:0008150 biological_process GO:0050793 regulation of developmental process More ... |
Strongylocentrotus purpuratus | 4v6w_AW(88) | Phyre | 1728593 | |||||
| P33316 | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediat More ... |
GO:0070062; C:extracellular exosome; IDA:UniProtKB. GO:0005739; C:mitochondrion; More ... |
RNA binding protein. |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Homo sapiens | 3ehw_A(100) | 1q5h_A/B/C (100), 1q5u_X/Y/Z (100), 2hqu_A/B/C (100), 3ara_A/B/C (100), 3arn_A/B More ... | Phyre | 26520658 | ||||
| P34756 | Inositol P kinase EC:2.7.1.150 | Inositol biosynthesis |
GO:0010008; C:endosome membrane; IDA:SGD. GO:0000329; C:fungal-type vacuole memb More ... |
Transcriptional regulation |
GO:0008150 biological_process GO:0050789 regulation of biological process GO:004 More ... |
Saccharomyces cerevisiae | Phyre | 10720331 | ||||||
| P34760 | cPrxI (Peroxiredoxin TSA1) EC:1.11.1.15 | Cytoplasmic peroxiredoxin (Peroxidase) |
GO:0005737; C:cytoplasm; IDA:SGD. GO:0005829; C:cytosol; IDA:SGD. GO:0005844; C: More ... |
Chaperon & Phospholipase aiPLA2 |
GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0006457; P:protein folding; IEA: More ... |
Saccharomyces cerevisiae | 3sbc_A(99) | 3sbc_A/B/C/D/E/F/G/H/I/J (100) | Phyre | 15163410 | ||||
| P34788 | S18 (40S ribosomal protein S18) | Ribosomal protein |
GO:0005618; C:cell wall; IDA:TAIR. GO:0005829; C:cytosol; IDA:TAIR. GO:0022626; More ... |
Regulation of development (mutation cause pointed first leaves instead of round More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Arabidopsis thaliana | 4v3p_SM(88) | Phyre | 7913892 | |||||
| P34823 | Eukaryotic elongation factor 1a (eEF-1A) | Protein synthesis (GTP-dependentbinding of amino-acyl-tRNA at theribosome accept More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Cytoskeleton structure regulation | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Carrot (Daucus carota), maize, rice and probably Arabidopsis | 5lzs_jj(78) | Phyre | 9390440 | |||||
| P34896 | Serine hydroxymethyltransferase, cytosolic | Interconversion of serine and glycine. |
GO:0005737; C:cytoplasm; IDA:HPA. GO:0005829; C:cytosol; IDA:UniProtKB. GO:00700 More ... |
Binds mRNA binds the 5' untranslated region (UTR) of its own mRNA |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | Smith-Magenis syndrome (omim:182290) | Pyridoxal Phosphate, Tetrahydrofolic acid, Glycine, Mimosine, Triglu-5-Formyl-Te More ... | 1bj4_A(99) | 1bj4_A (100), 6fl5_A/D/G/J (100), 6m5w_A (100), 7rjl_C/D (100), 7rjp_B (100), 8a More ... | Phyre | 10995219 | ||
| P34960 | Macrophage metalloelastase | May be involved in tissue injury and remodeling. Has significant elastolytic act More ... |
GO:0005576; C:extracellular region; TAS:Reactome. GO:0005578; C:proteinaceous ex More ... |
Promotes transcription binds to the NFKBIA promoter |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compoun More ... |
Mus musculus | 1y93_A(70) | Phyre | 24784232 | |||||
| P35222 | Catenin beta-1 | Nucleus/Transcription factor |
GO:0005912; C:adherens junction; IDA:UniProtKB. GO:0045177; C:apical part of cel More ... |
Cytoplasm/Interaction with catenins and actins |
GO:0003674 molecular_function GO:0005488 binding GO:0044877 macromolecular compl More ... |
Homo sapiens | Colorectal cancer (CRC) (omim:114500) | Urea | 4ev8_A(100) | 1g3j_A/C (100), 1jdh_A (100), 1jpw_A/B/C (100), 1luj_A (100), 1p22_C (100), 1qz7 More ... | Phyre | 26499805 | ||
| P35268 | L22 (60S ribosomal protein L22) | Ribosomal protein |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; TAS:Reactome. GO: More ... |
Forms ribonucleoprotein particles (RNP) with Epstein-Barr-encoded small RNA in B More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | Monoallelically inactivated in 10% of Tcell lymphoblastic leukemia (omim:180474) | 3j3b_U(100) | 4ug0_LU (100), 4v6x_CU (100), 5aj0_AU (100), 5lks_LU (100), 5t2c_O (100), 6ip5_2 More ... | Phyre | 8159770 | |||
| P35635 | 60 kDa chaperonin | Chaperone |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Induce apoptosis in cultured vascular endothelial cells | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Bartonella baciliformis | 1iok_A(81) | Phyre | 16481529 | |||||
| P35846 | Folate receptor alpha Folr1 | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-me More ... | GO:0031362; C:anchored component of external side of plasma membrane; ISS:UniPro More ... | Transcription factor |
GO:0003674 molecular_function GO:0003676 nucleic acid binding GO:0001067 regula More ... |
Mus musculus | 5izq_A(83.1) | Phyre | 23243496 | |||||
| P36024 | Hal3 (Halotolerance protein HAL3) | Inhibitor of Protein Phosphatase PPZ1 (involved in halotolerance) (Monomer) |
GO:1990143; C:CoA-synthesizing protein complex; IDA:SGD. GO:0005737; C:cytoplasm More ... |
Coenzyme A decarboxylase (heterotrimer with VHS3) EC:4.1.1.41 |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Saccharomyces cerevisiae | 1qzu_A(68) | Phyre | 19915539 | |||||
| P36241 | L19 (60S ribosomal protein L19) | Ribosomal protein |
GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central. GO:0022626; C:c More ... |
Regulation of development (required for normal wing blade development) | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Drosophila melanogaster | 4v6w_CR(100) | 4v6w_CR (100), 6xu6_CR (100), 6xu7_CR (100), 6xu8_CR (100) | Phyre | 8297785 | ||||
| P36683 | Aconitate hydratase 2 | Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well a More ... |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0047456; F:2-methylisocitrate dehydratase More ... |
It becomes a regulatory RNA-binding protein when intracellular iron becomes scar More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Escherichia coli | 1l5j_A(100) | 1l5j_A/B (100) | Phyre | 25092924 | ||||
| P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | Glycogen metabolism, muscle contractility, and protein synthesis |
GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell. GO:0000777; C:condensed ch More ... |
May play an important role in dephosphorylating substrates such as the postsynap More ... |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic co More ... |
Homo sapiens | Triosephosphate isomerase deficiency (TPID) (omim:615512) | 3e7a_A(98) | 1it6_A/B (100), 1jk7_A (100), 1u32_A (100), 2bcd_A (100), 2bdx_A (100), 4ut2_A/B More ... | Phyre | 26520658 | |||
| P36897 | TGF-beta receptor type-1 |
Cell surface/Type I transmembrane protein" |
GO:0005923; C:bicellular tight junction; IDA:UniProtKB. GO:0005623; C:cell; ISS: More ... |
Nucleus/Participates in gene regulation |
GO:0008150 biological_process GO:0065007 biological regulation GO:0008152 metabo More ... |
Homo sapiens | Loeys-Dietz syndrome 1 (LDS1) (omim:609192) | 3kcf_A(100) | 1b6c_B/D/F/H (100), 1ias_A/B/C/D/E (100), 1py5_A (100), 1rw8_A (100), 1vjy_A (10 More ... | Phyre | ||||
| P36969 | Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | Protects cells against membrane lipid peroxidation and cell death. Required for More ... |
GO:0005829; C:cytosol; TAS:Reactome. GO:0070062; C:extracellular exosome; IDA:Un More ... |
Upstream regulator of a novel form of non-apoptotic cell death, called ferroptos More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0009987 cellul More ... |
Homo sapiens | Spondylometaphyseal dysplasia, Sedaghatian type (SMDS) (omim:250220) | Glutathione | 2obi_A(99) | 2gs3_A (100), 2obi_A (100), 5h5q_A (100), 5h5r_A (100), 5h5s_A (100), 6elw_A (10 More ... | ITasser | 25922076 | ||