| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P10809 | 60 kDa heat shock protein, mitochondrial | Implicated in mitochondrial protein import and macromolecular assembly. May faci More ... |
GO:0009986; C:cell surface; IDA:UniProtKB. GO:0005905; C:clathrin-coated pit; ID More ... |
Immunomodulator Receptor for HDL |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | Spastic paraplegia 13, autosomal dominant (omim:605280) | Not available | 4pj1_A(100) | 4pj1_A/B/C/D/E/F/G/H/I/J/K/L/M/N (100), 6ht7_A/B/C/D/E/F/G/H/I/J/K/L/M/N (100), More ... | Phyre | 22143554 | ||
| P11089 | Flagellar filament 41 kDa core protein | Component of the core of the flagella. |
GO:0009420; C:bacterial-type flagellum filament; IEA:InterPro. GO:0055040; C:per More ... |
Bound specifically to galactosylceramide |
GO:0003674 molecular_function GO:0005488 binding GO:0097367 carbohydrate derivat More ... |
Borrelia burgdorferi | 1io1_A(54) | Phyre | 9234772 | |||||
| P11325 | Leucine--tRNA ligase, mitochondrial | ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). |
GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005739; C:mitocho More ... |
Intron splicing, RNA splicing group I intron splicing | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 1h3n_A(73) | Phyre | 22383526 | |||||
| P11415 | Zeta-crystallin EC:1.6.5.5 | Lens crystallin |
GO:0005829; C:cytosol; ISS:UniProtKB. GO:0070062; C:extracellular exosome; IEA:E More ... |
NADPH: quinone oxidoreductase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Cavia porcellus | 1yb5_A(83) | Phyre | 2462567 | |||||
| P11980 | Pyruvate kinase EC:2.7.1.40 | Converts phosphoenolpyruvate (PEP) to pyruvate (glycolysis) |
GO:0005913; C:cell-cell adherens junction; IEA:Ensembl. GO:0070062; C:extracellu More ... |
Cytosolic thyroid hormone binding protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0060089; F:mo More ... |
Rattus norvegicus | 3srf_A(97) | Phyre | 1883388 | |||||
| P12063 | Tyrosyl tRNA synthetase EC:6.1.1.1 | Tyrosyl tRNA synthetase |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0005759; C:mitochondrial matrix; IEA:U More ... |
Promotes folding of group I introns |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Neurospora crassa | 1y42_X(100) | 1y42_X (100), 2rkj_A/B/E/F/I/J/M/N (100), 4ojm_X (100) | Phyre | 8648621 | ||||
| P12281 | Molybdopterin molybdenumtransferase | Catalyzes the insertion of molybdate into adenylated molybdopterin with the conc More ... |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0046872; F:metal ion binding; IEA:UniProtK More ... |
Neuroreceptor clustering |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Escherichia coli | 2nqr_A(99) | 1fc5_A/B (100), 1g8l_A/B (100), 1g8r_A/B (100), 2nqk_A/B (100), 2nqm_A/B (100), More ... | Phyre | 28284029 | ||||
| P12282 | Molybdopterin-synthase adenylyltransferase | Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine More ... |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. More ... |
Interaction with URM1 |
GO:0003674 molecular_function GO:0003824 catalytic activity GO:0016874 ligase ac More ... |
Escherichia coli | 1jw9_B(100) | 1jw9_B (100), 1jwa_B (100), 1jwb_B (100) | Phyre | 28284029 | ||||
| P12425 | Glutamine synthase EC:6.3.1.2 | Synthesis of Glutamine |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Control of gene expression. When glutamine levels are high the inhibited enzyme More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0008152 metabo More ... |
Bacillus subtilis | 4s0r_A(100) | 4lnf_A/B/C/D/E/F/G/H/I/J/K/L (100), 4lni_A/B/C/D/E/F/G/H/I/J/K/L (100), 4lnk_A/B More ... | Phyre | 18086213 | ||||
| P12685 | High-affinity potassium transport protein | This protein is required for high-affinity potassium transport. |
GO:0005887; C:integral component of plasma membrane; IEA:InterPro. GO:0045121; C More ... |
Mitochondrial Import of tRNA. | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 5hi9.1.A(10) | Phyre | 25918939 | |||||
| P12830 | E-cadherin | Cell surface/Involved in cell adhesion |
GO:0015629; C:actin cytoskeleton; IDA:BHF-UCL. GO:0016235; C:aggresome; IDA:HPA. More ... |
Nucleus/Gene regulation |
GO:0008150 biological_process GO:0065007 biological regulation GO:0008152 metabo More ... |
Homo sapiens | Hereditary diffuse gastric cancer (HDGC) (omim:137215) | 2o72_A(100) | 1o6s_B (100), 2o72_A (100), 2omt_B (100), 2omu_B (100), 2omv_B (100), 2omx_B (10 More ... | Phyre | 26499805 | |||
| P13010 | Ku70/Ku80 | Single stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome t More ... |
GO:0005829; C:cytosol; TAS:Reactome. GO:0043564; C:Ku70:Ku80 complex; IDA:UniPro More ... |
Extracellular protease (function at the cell surface is likely to be important i More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Colon cancer (omim:194364) | 1jeq_B(100) | 1jeq_B (100), 1jey_B (100), 1q2z_A (100), 1rw2_A (100), 3rz9_B (100), 5y3r_B (10 More ... | Phyre | 15738653 | |||
| P13299 | I-TevI endonuclease | Homing endonuclease |
GO:0003677; F:DNA binding; IEA:InterPro. GO:0004519; F:endonuclease activity; IE More ... |
Transcriptional autorepressor |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Enterobacteria phage T4 | 1i3j_A(100) | 1i3j_A (100), 1ln0_A/B (100), 1mk0_A (100), 1t2t_A (100) | Phyre | 15361856 | ||||
| P13376 | Phosphoglucose isomerase EC:5.3.1.9 | Catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate (glyco More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004347; F:glucose-6-phosphat More ... |
It has been shown to have both autocrine motility factor and neuroleukin activit More ... |
GO:0003674 molecular_function GO:0050794 regulation of cellular process GO:00230 More ... |
Geobacillus stearothermophilus | 1b0z_A(100) | 1b0z_A (100), 1c7q_A (100), 1c7r_A (100), 2pgi_A (100) | Phyre | 10318897 | ||||
| P13569 | CFTR chloride channel (Cystic fibrosis transmembrane conductance regulator) EC:3 More ... | Involved in the transport of chloride ions |
GO:0016324; C:apical plasma membrane; IDA:UniProtKB. GO:0016323; C:basolateral p More ... |
Regulator of other epitelial anion channels (Regulator of Na+ channels) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0016247; F:ch More ... |
Homo sapiens | Congenital bilateral absence of vas deference (omim:277180) | Lubiprostone | 5u71_A(100) | 1xmi_A/B/C/D/E (100), 1xmj_A (100), 2bbo_A (100), 2bbs_A/B (100), 2bbt_A/B (100) More ... | Phyre | 7543698 | ||
| P13716 | Delta-aminolevulinic acid dehydratase EC:4.2.1.24 | Delta-aminolevulinic acid dehydratase |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0070062; C:extracellular exosome; IDA: More ... |
Proteasome inhibitory subunit |
GO:0003674 molecular_function GO:0005488 binding GO:0044877 macromolecular compl More ... |
Homo sapiens | Porphyria, acute hepatic (omim:612740) | Aminolevulinic acid | 1e51_A(100) | 1e51_A/B (100), 1pv8_A/B (100), 5hms_A/B (100), 5hnr_A/B (100) | Phyre | 8175643 | ||
| P13743 | L-lactate dehydrogenase B chain | Lactate dehydrogenase. |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004459; F:L-lactate dehydrog More ... |
In duck lens LDH-B is used as a crystallin: epsilon-crystallin. |
GO:0003674 molecular_function GO:0005198 structural molecule activity GO:0005212 More ... |
Anas platyrhynchos | 1i0z_A(88) | Phyre | 3174623 | |||||
| P13922 | Bifunctional dihydrofolate reductase-thymidylate synthase | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymid More ... |
GO:0004146; F:dihydrofolate reductase activity; IEA:UniProtKB-EC. GO:0004799; F: More ... |
binds DHFR mRNA regulation of DHFR synthesis methotrexate inhibits interaction |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compoun More ... |
Plasmodium falciparum | Megaloblastic anemia due to dihydrofolate reductase deficiency (omim:613839) | 1j3k_C(100) | 1j3i_A/B (100), 1j3j_A/B (100), 1j3k_A/B (100), 3dg8_A/B (100), 3dga_A/B (100), More ... | Phyre | 8490020 | |||
| P14120 | 60S ribosomal protein L30 | Component of the ribosome large subunit (60S) |
GO:0005737; C:cytoplasm; IDA:SGD. GO:0022625; C:cytosolic large ribosomal subuni More ... |
Inhibits the splicing of the transcript of its own gene, RPL32 | GO:0008150 biological_process GO:0008380 RNA spl More ... | Saccharomyces cerevisiae | 1t0k_B(100) | 1ck2_A (100), 1cn7_A (100), 1nmu_B/D (100), 1t0k_B (100), 3j6x_70 (100), 3j6y_70 More ... | Phyre | 2040015 | ||||
| P14324 | Farnesyl pyrophosphate synthase | Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl More ... |
GO:0005737; C:cytoplasm; IBA:GO_Central. GO:0005829; C:cytosol; IDA:HPA. GO:0005 More ... |
RNA binding protein. FPP also serves as substrate for protein farnesylation and More ... |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Homo sapiens | Porokeratosis 9, multiple types (POROK9) (omim:616631) |
<a href=""https://www.drugbank.ca/biodb/bio_entities/BE0000776"">Pamidronate Zol More ... |
4nua_A(99) | 1yq7_A (100), 1yv5_A (100), 1zw5_A (100), 2f7m_F (100), 2f89_F (100), 2f8c_F (10 More ... | Phyre | 26520658 | ||
| P14618 | Pyruvate kinase PKM | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phospho More ... |
GO:0005913; C:cell-cell adherens junction; IDA:BHF-UCL. GO:0005929; C:cilium; IE More ... |
It would act as potential sites of recognition and/or binding for ZP glycoprotei More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Hepatocellular carcinoma, Carcinoma, Osteoporosis | <a href="http://www.drugbank.ca/biodb/bio_entities/BE0000088"target=_blank">Pyru More ... | 2g50_A(96) | 1t5a_A/B/C/D (100), 1zjh_A (100), 3bjf_A/B/C/D (100), 3bjt_A/B/C/D (100), 3g2g_A More ... | Phyre | 23355646 | ||
| P14755 | Lambda lens crystallins EC:1.1.1.45 | Lens crystallin |
GO:0005829; C:cytosol; IDA:UniProtKB. GO:0003857; F:3-hydroxyacyl-CoA dehydrogen More ... |
L-Gulonate-3-dehyddrogenase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Oryctolagus cuniculus | 3ado_A(100) | 3ado_A (100), 3adp_A (100) | Phyre | 2462567 | ||||
| P15144 | CD13 (Aminopeptidase N) | Broad specificity aminopeptidase. Plays a role in the final digestion of peptide More ... |
GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. GO:0005793; C:endoplasmic reticulu More ... |
Peptide cleavage (enzymatic regulation of peptides/tumor cell invasion/different More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Urinary Bladder Neoplasms, Dermatitis, Allergic Contact | [(125)I] RB129 | 4fyq_A(100) | 4fyq_A (100), 4fyr_A (100), 4fys_A (100), 4fyt_A (100), 5lhd_A/B/C/D (100), 6atk More ... | Phyre | 18603472 | ||
| P15291 | Beta-1,4-galactosyltransferase 1 | The Golgi complex form catalyzes the production of lactose in the lactating mamm More ... |
GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB. GO:0031526; C:brush bo More ... |
Lactose synthase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Homo sapiens | Congenital disorder of glycosylation, type IId (omim:607091) | N-Acetyl-D-glucosamine, 6-Aminohexyl-Uridine-C1,5'-Diphosphate, Di(N-Acetyl-D-Gl More ... | 2fy7_A(99) | 2ae7_A/B/C (100), 2aec_A/B/C (100), 2aes_A/B/C (100), 2agd_A/B/C (100), 2ah9_A/B More ... | Phyre | 5238979 | ||
| P15336 | ATF2 protein (Cyclic AMP-dependent transcription factor) EC:2.3.1.48 | Transcription factor (stimulates CRE (cAMP responsive element)-dependent transcr More ... |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005741; C:mitochondrial outer membra More ... |
DNA damage response | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | cancer (omim:123811) | Midostaurin | 1t2k_D(98) | 1bhi_A (100), 1t2k_D (100), 4h36_B (100), 6zqs_B (100), 6zr5_C/D (100) | Phyre | 15916964 | ||
| P15531 | Nucleoside diphosphate kinase A | Major role in the synthesis of nucleoside triphosphates other than ATP. |
GO:0005737; C:cytoplasm; TAS:UniProtKB. GO:0005829; C:cytosol; IDA:UniProtKB. GO More ... |
RNA binding protein. Involved in cell proliferation, differentiation and develop More ... |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Homo sapiens |
<a href=""https://www.drugbank.ca/biodb/bio_entities/BE0003106"">Lamivudine Teno More ... |
1ucn_A(99) | 1jxv_A/B/C/D/E/F (100), 1ucn_A/B/C (100), 2hvd_A/B/C (100), 2hve_A/B/C (100), 3l More ... | Phyre | 26520658 | |||
| P15559 | NAD(P)H dehydrogenase [quinone] 1 | Detoxification pathways and vitamin K-dependent γ-carboxylation of glutamat More ... |
GO:0005737; C:cytoplasm; TAS:ProtInc. GO:0005829; C:cytosol; IDA:CAFA. GO:007006 More ... |
RNA binding protein. |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Homo sapiens | Cancer |
<a href=""https://www.drugbank.ca/biodb/bio_entities/BE0001184"">Dicoumarol Flav More ... |
1kbq_A(100) | 1d4a_A/B/C/D (100), 1dxo_A/B/C/D (100), 1gg5_A/B/C/D (100), 1h66_A/B/C/D (100), More ... | Phyre | 26520658 | ||
| P16402 | Histone H1 | Histone (Histone H1 protein binds to linker DNA between nucleosomes forming the More ... |
GO:0000790; C:nuclear chromatin; IDA:UniProtKB. GO:0005719; C:nuclear euchromati More ... |
Thyroglobulin receptor |
GO:0005488; F:binding. Synonyms: ligand. GO:0005515; F:protein binding. Synonyms More ... |
Mus musculus | 1ghc_A(89) | 7xx5_U (100) | Phyre | 9664069 | ||||
| P16858 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005829; C:cytosol; ISS:UniProtKB. GO More ... |
under the contrary condition of intracellular iron excess, cells switch the isof More ... | GO:1903414(iron cation export) | Mus musculus | 1u8f_O(96) | 6lgj_A/B/C/D (100), 6lgk_A/B/C/D (100), 6lgm_A/B/C/D (100) | Phyre | 25074810 | ||||
| P16951 | Cyclic AMP-dependent transcription factor ATF-2 | Transcriptional activator which regulates the transcription of various genes, in More ... |
GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0016020; C:membrane; IDA:MGI. GO:0005 More ... |
Recruiting Mre11 to IR-induced foci (IRIF) in the DNA damage response. |
GO:0009987 cellular process GO:0050789 regulation of biological process GO:00508 More ... |
Mus musculus | 1bhi_A(100) | Phyre | 15916964 | |||||
| P17050 | Alpha-N-acetylgalactosaminidase | Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glyco More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005576; C:extracellular region; IDA:MT More ... |
Immunosuppression. Inhibition of GcMAF-related macrophage activation. |
GO:0048523 negative regulation of cellular process GO:0050865 regulation of cell More ... |
Homo sapiens | Schindler disease, type III (omim:609241) | 3h53_A/B (100), 3h54_A/B (100), 3h55_A/B (100), 3igu_A/B (100), 4do4_A/B (100), More ... | Phyre | 12062184 | ||||
| P17256 | Mevalonate kinase | May be a regulatory site in cholesterol biosynthetic pathway. |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; IDA:RGD. GO:00057 More ... |
mRNA binding cytosolic luteinizing hormone receptor mRNA binding protein increas More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Rattus norvegicus | 1kvk_A(100) | 1kvk_A (100), 2r42_A (100) | Phyre | 9553128 | ||||
| P18074 | ERCC2 - TFIIH basal transcription factor complex helicase XPD subunit | DNA helicase involved in the repair of DNA damaged by exposure to ultraviolet li More ... |
GO:0000439; C:core TFIIH complex; IEA:Ensembl. GO:0005737; C:cytoplasm; IDA:UniP More ... |
It is also a subunit of TFIIH, a basal transcription factor |
GO:0009058 biosynthetic process GO:0046483 heterocycle metabolic process GO:0050 More ... |
Homo sapiens | Xeroderma pigmentosum, group D (omim:278730) | 5ivw_W(100) | 5ivw_W (100), 5iy6_W (100), 5iy7_W (100), 5iy8_W (100), 5iy9_W (100), 5of4_B (10 More ... | Phyre | 14726016 | |||
| P18124 | L7 | Ribosomal protein |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; TAS:Reactome. GO: More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Homo sapiens | Systemic lupus erythematosus (omim:604166) | 4d5y_F(100) | 4ug0_LF (100), 4v6x_CF (100), 5aj0_AF (100), 5lks_LF (100), 5t2c_M (100), 6ip5_2 More ... | Phyre | 7862521 | |||
| P18266 | Glycogen synthase kinase 3Beta | Sugar metabolism |
GO:0030424; C:axon; IDA:RGD. GO:0030877; C:beta-catenin destruction complex; IDA More ... |
Role in embryonic development | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Rattus norvegicus | 5air_A(99) | Phyre | 22143554 | |||||
| P18754 | Regulator of chromosome condensation | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP More ... |
GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB. GO:0005737; C:cytopla More ... |
Involved in the regulation of onset of chromosome condensation in the S phase. B More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0003682 chromatin binding pr More ... |
Homo sapiens | Raynaud disease | 1a12_A(100) | 1a12_A/B/C (100), 1i2m_B/D (100), 5e1b_D/E (100), 5e1d_D/E (100), 5e1m_D/E (100) More ... | Phyre | 26793706 | |||
| P19338 | Nucleolin | Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is foun More ... |
GO:0005938; C:cell cortex; IDA:UniProtKB. GO:0036464; C:cytoplasmic ribonucleopr More ... |
Regulates (decreases) translation of p53 tumor suppressor protein binds 5' UTR o More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | Cancer (omim:164035) | Not available | 2fc8_A(100) | 2fc8_A (100), 2fc9_A (100), 2krr_A (100) | Phyre | 16213212 | ||
| P19367 | Hexokinase | Glycolysis |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0045121; C:membrane raft; IEA:Ensembl. More ... |
Controlling apoptosis | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Hemolytic anemia due to hexokinase deficiency (omim:235700) | Alpha-D-Glucose-6-Phosphate, Beta-D-Glucose, Phosphoaminophosphonic Acid-Adenyla More ... | 1hkb_A(100) | 1cza_N (100), 1dgk_N (100), 1hkb_A/B (100), 1hkc_A (100), 1qha_A/B (100), 4f9o_A More ... | Phyre | 22143554 | ||
| P19882 | Heat shock protein 60, mitochondrial | Mitochondrial chaperone |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0005743; C:mitochondrial inner membran More ... |
Stabilization active DNA units |
GO:0008150:P;biological_process GO:0065007:P: biological regulation GO:0065008;P More ... |
Saccharomyces cerevisiae | 1grl_A(63) | Phyre | 14597775 | |||||
| P19889 | 60S acidic ribosomal protein P0 | P0 ribosomal protein part of the 60S subunit. Ribosomal protein P0 is the functi More ... |
GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central. GO:0022626; C:c More ... |
Apurinic-apyrimidinic endonuclease, enzyme functions in DNA repair act on AP DNA More ... |
GO:0003674 molecular_function GO:1901360 organic cyclic compound metabolic proce More ... |
Drosophila melanogaster | 3j92_s(72.8) | Phyre | 8932386 | |||||
| P19956 | 54S ribosomal protein L44, mitochondrial | Ribosomal protein |
GO:0005762; C:mitochondrial large ribosomal subunit; IDA:SGD. GO:0003735; F:stru More ... |
It supports abiotic stress resistance |
GO:0008150 biological_process GO:0050896 response to stimulus GO:0009628 respons More ... |
Saccharomyces cerevisiae | 1rod.1.A(14) | Phyre | 24814782 | |||||
| P19971 | Thymidine phosphorylase EC:2.4.2.4 | Phosphorylates thymidine to produce thymine and 2-deoxy-alpha-D-ribose 1-phospha More ... |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0004645; F:phosphorylase activity; IBA More ... |
Platelet-derived endothelial cell growth factor |
GO:0008150 biological_process GO:0050789 regulation of biological process GO:000 More ... |
Homo sapiens | Mitochondrial DNA depletion syndrome 1 (omim:603041) | Uridine | 2wk5_A(100) | 1uou_A (100), 2j0f_A/B/C/D (100), 2wk5_A/B/C/D (100), 2wk6_A/B (100) | Phyre | 1570012 | ||
| P20967 | Alfa-ketoglutarate dehydrogenase EC:1.2.4.2 | TCA cycle enzyme |
GO:0042645; C:mitochondrial nucleoid; IDA:SGD. GO:0009353; C:mitochondrial oxogl More ... |
Mitochondrial DNA maintenance | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 2xt6_A(67) | Phyre | 10869431 | |||||
| P21399 | Cytoplasmatic aconitate hydratase/IRP1 EC:4.2.1.3 | Catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aco More ... |
GO:0005737; C:cytoplasm; IMP:CAFA. GO:0005829; C:cytosol; IDA:HGNC. GO:0005783; More ... |
mRNA binding protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | Myopathy with lactic acidosis, hereditary (omim:255125) | Not available | 2b3x_A(100) | 2b3x_A (100), 2b3y_A/B (100) | Phyre | 17698960 | ||
| P21458 | DNA translocase SpoIIIE | Plays an essential role during sporulation. Required for the translocation of th More ... |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. GO:0005886; C:pl More ... |
Membrane fusion |
GO:0008150 biological_process GO:0071840 cellular component organization or biog More ... |
Bacillus subtilis | 2iut_A(71.4) | Phyre | 22014899 | |||||
| P21912 | Succinate dehydrogenase EC:1.3.99.1 | TCA cycle enzyme |
GO:0070062; C:extracellular exosome; IDA:UniProtKB. GO:0005743; C:mitochondrial More ... |
Tumor supression (it should play specific tumor-suppressing roles, directly or i More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo Sapiens | Pheochromocytoma (omim:171300) | Succinic acid, Chlormerodrin | 4ytp_B(96) | 7kcl_C (100), 7kcm_C (100), 7klu_B/C (100), 7klv_B (100), 8gs8_B (100) | Phyre | 11404820 | ||
| P21980 | Protein-glutamine gamma-glutamyltransferase 2 | Cytoplasm/Catalyzes protein cross-linking |
GO:0005829; C:cytosol; IDA:UniProtKB. GO:0005783; C:endoplasmic reticulum; IEA:G More ... |
(1) Nucleus/Regulates gene expression; (2) Extracellular region/Cell adhesion an More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0008152 metabo More ... |
Homo sapiens | Cancer | L-Glutamine, Guanosine-5'Diphosphate | 2q3z_A(99) | 1kv3_A/B/C/D/E/F (100), 2q3z_A (100), 3ly6_A/B/C (100), 3s3j_A (100), 3s3p_A (10 More ... | Phyre | 26499805 | ||
| P22090 | S4 (40S ribosomal protein S4, Y isoform 1) | Ribosomal protein |
GO:0005829; C:cytosol; TAS:Reactome. GO:0022627; C:cytosolic small ribosomal sub More ... |
Regulation of development (Turner syndrome: female gonadal insufficiency) | Homo sapiens | Turner syndrome (omim:470000) | 4d5l_E(100) | 5aj0_BE (100), 5flx_E (100), 6olg_BE (100), 6olz_BE (100) | Phyre | 2124517 | ||||
| P22512 | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0020015; C:glycosome; IEA:UniProtKB-SubCell. GO:0004365; F:glyceraldehyde-3-p More ... |
Flagellar protein |
GO:0080086 (stamen filament development) GO:0005200 (structural constituent of c More ... |
Trypanosoma brucei brucei | 2x0n_A(100) | 2x0n_A/B/O/P/Q/R (100), 3cvn_B (100) | Phyre | 25050549 | ||||
| P23202 | Ure2 (Transcriptional regulator URE2) EC:1.11.1.9 | Regulator of nitrogen catabolite repression |
GO:0005829; C:cytosol; IDA:SGD. GO:0004602; F:glutathione peroxidase activity; I More ... |
Glutathione peroxidase activity |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Saccharomyces cerevisiae | 1g6w_A(100) | 1g6w_A/B/C/D (100), 1g6y_A/B (100), 1hqo_A/B (100), 1jzr_A/B/C/D (100), 1k0a_A/B More ... | Phyre | 12562760 | ||||