| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| O87712 | Chaperone protein DnaK | Chaperone |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; I More ... |
Adhesion to host, unknow receptor. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Coxiella burnetti | 1dkg_D(82) | Phyre | 20045689 | |||||
| O94811 | Tubulin polymerization-promoting protein | May play a role in the polymerization of tubulin into microtubules, microtubule More ... |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; IDA:HPA. GO:0005 More ... |
Cell survival in cáncer or cell apoptosis in neurodegenerative diseases. |
GO:0008150 biological_process GO:0009987 cellular process GO:0044699 single-orga More ... |
Homo sapiens |
Cancer. Parkinson. Multiple System Atrophy. |
1wlm_A(63) | Phyre | 28271739 | ||||
| O94811 | Tubulin polymerization-promoting protein | May play a role in the polymerization of tubulin into microtubules, microtubule More ... |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005874; C:microtubule; IEA:Ensembl. More ... |
Interaction with alfa-synuclein (May be involved in the regulation of dopamine r More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | 1wlm_A(63) | Phyre | 24463170 | |||||
| O95396 | Adenylyltransferase and sulfurtransferase MOCS3 | Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of cyto More ... |
GO:0005829; C:cytosol; IDA:UniProtKB. GO:0005524; F:ATP binding; IEA:UniProtKB-K More ... |
Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating More ... |
GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL. GO:00 More ... |
Homo sapiens | 3I2V | 3i2v_A (100) | Phyre | 28284029 | ||||
| O95400 | CD2BP2 (CD2 antigen cytoplasmic tail-binding protein 2) | Spliceosome protein |
GO:0005737; C:cytoplasm; IDA:HPA. GO:0005654; C:nucleoplasm; IDA:BHF-UCL. GO:000 More ... |
Binds CD2 receptor |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | 1syx_B(100) | 1gyf_A (100), 1l2z_A (100), 1syx_B/D/F (100), 4bws_C/F (100), 8q7q_G (100), 8q7v More ... | Phyre | 17467737 | ||||
| O95997 | Securin | Inhibition of separase |
GO:0005737; C:cytoplasm; TAS:ProtInc. GO:0005829; C:cytosol; TAS:Reactome. GO:00 More ... |
Activation (chaperoning) of separase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0030234; F:en More ... |
Homo sapiens | Cancer, Psoriasis, Glomerulonephritis | 7nj0_A (100), 7nj1_B (100) | Phyre | 12123570 | ||||
| O96007 | Molybdopterin synthase catalytic subunit | Catalytic subunit of the molybdopterin synthase complex, a complex that catalyze More ... |
GO:0005829; C:cytosol; IDA:UniProtKB. GO:0019008; C:molybdopterin synthase compl More ... |
Interaction with MBIP |
GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL. GO:00 More ... |
Homo sapiens | Molybdenum cofactor deficiency, complementation group B (MOCODB) (omim:252160) | 4ap8_A(100) | 4ap8_A/B/C/D (100), 5mpo_C/D (100) | Phyre | 28284029 | |||
| P00004 | Cytochrome c | Electron carrier protein. The oxidized form of the cytochrome c heme group can a More ... |
GO:0005829; C:cytosol; ISS:UniProtKB. GO:0005758; C:mitochondrial intermembrane More ... |
Binding to apoptosis protease activation factor-1 (Apaf-1) promotes apoptosis re More ... |
GO:0008150;P:biological_process GO:0065007;P: biological regulation GO:0009987;P More ... |
Equus caballus | 3jbt_B(100) | 1akk_A (100), 1crc_A/B (100), 1fi7_A (100), 1fi9_A (100), 1giw_A (100), 1hrc_A ( More ... | Phyre | 12372987 | ||||
| P00044 | Cytochrome c iso-1 | Electron carrier protein. The oxidized form of the cytochrome c heme group can a More ... |
GO:0005758; C:mitochondrial intermembrane space; IDA:SGD. GO:0070469; C:respirat More ... |
Binding to apoptosis protease activation factor-1 (Apaf-1) promotes apoptosis re More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0009987 cellul More ... |
Saccharomyces cerevisiae | 4n0k_A(99) | 1chh_A (100), 1chi_A (100), 1chj_A (100), 1cie_A (100), 1cif_A (100), 1cig_A (10 More ... | Phyre | 12372987 | ||||
| P00338 | Lactate dehydrogenase | Pyruvate fermentation to lactate. |
GO:0005913; C:cell-cell adherens junction; IDA:BHF-UCL. GO:0005829; C:cytosol; T More ... |
Protein translation factor | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Glycogen storage disease XI (omim:612933) | NADH, Etheno-Nad, Nicotinamide, Oxamic Acid | 4zvv_A(100) | 1i10_A/B/C/D/E/F/G/H (100), 4ajp_A/B/C/D (100), 4jnk_A/B/C/D (100), 4l4r_A/H (10 More ... | Phyre | 22143554 | ||
| P00368 | Glutamate dehydrogenase 1, mitochondrial | Glutamate dehydrogenase |
GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005524; F:ATP bin More ... |
Histone H3 specific protease activity |
GO:0008150 biological_process GO:0008152 metabolic process GO:0006807 nitrogen c More ... |
Gallus gallus | 1hwx_A(93) | ITasser | 23856561 | |||||
| P00505 | Aspartate aminotransferase, mitochondrial | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynur More ... |
GO:0009986; C:cell surface; IEA:Ensembl. GO:0070062; C:extracellular exosome; ID More ... |
RNA binding protein. |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Homo sapiens | <a href=""https://www.drugbank.ca/biodb/bio_entities/BE0000383"">L-Aspartic Acid More ... | 3pd6_A(95) | 5ax8_A/B/C/D (100), 8skr_A/C (100) | Phyre | 26520658 | |||
| P00533 | Epidermal growth factor receptor | Cell surface/Membrane receptor tyrosine kinase for EGF |
GO:0016324; C:apical plasma membrane; IEA:Ensembl. GO:0016323; C:basolateral pla More ... |
Nucleus/Co-transcription factor |
GO:0003674 molecular_function GO:1903506 regulation of nucleic acid-templated tr More ... |
Homo sapiens | Lung cancer (LNCR) (omim:211980) | Cetuximab, Trastuzumab, Lidocaine, Gefitinib, Erlotinib, Lapatinib, Panitumumab More ... | 3poz_A(100) | 1ivo_A/B (100), 1m14_A (100), 1m17_A (100), 1mox_A/B (100), 1nql_A (100), 1xkk_A More ... | Phyre | 26499805 | ||
| P00558 | Phosphoglycerate kinase EC:2.7.2.3 | It converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate (glycolysis More ... |
GO:0005829; C:cytosol; TAS:Reactome. GO:0070062; C:extracellular exosome; IDA:Un More ... |
Plasmin reductase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Homo sapiens | Phosphoglycerate kinase deficiency, hepatocellular carcinoma, Renal cell carcino More ... | 2xe6_A(100) | 2wzb_A (100), 2wzc_A (100), 2wzd_A (100), 2x13_A (100), 2x14_A (100), 2x15_A (10 More ... | Phyre | 11130727 | |||
| P00711 | Lactose synthetase (Alpha-lactalbumin) | Regulatory subunit of lactose synthase |
GO:0005615; C:extracellular space; IDA:AgBase. GO:0005509; F:calcium ion binding More ... |
Galactosyltransferase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Bos Taurus | 1f6r_A(100) | 1f6r_A/B/C/D/E/F (100), 1f6s_A/B/C/D/E/F (100), 1hfz_A/B/C/D (100), 2g4n_A/B/C/D More ... | Phyre | 5238979 | ||||
| P00734 | Thrombin protease (Prothrombin) | Thrombin protease |
GO:0072562; C:blood microparticle; IDA:UniProtKB. GO:0005788; C:endoplasmic reti More ... |
Ligand for cell surface receptors |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0060089; F:mo More ... |
Homo sapiens | Stroke, ischemic (omim:601367) | Ximelegatran, Argatroban, Bivalirudin, Dabigatran, Lepirudin, SR-123781A, AZD083 More ... | 4hzh_A(100) | 1a2c_H (100), 1a3b_H (100), 1a3e_H (100), 1a46_H (100), 1a4w_H (100), 1a5g_H (10 More ... | Phyre | 1672265 | ||
| P00812 | Arginase EC:3.5.3.1 | Arginine hydrolysis |
GO:0005829; C:cytosol; IDA:SGD. GO:0004053; F:arginase activity; IDA:SGD. GO:003 More ... |
Inhibitor of ornithintranscarbamoylase |
GO:0008150 biological_process GO:0044281 small molecule metabolic process GO:006 More ... |
Saccharomyces cerevisiae | 4ity_A(73) | Phyre | 11946965 | |||||
| P00813 | Adenosine Deaminase | Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an More ... |
GO:0030054; C:cell junction; IEA:UniProtKB-SubCell. GO:0009986; C:cell surface; More ... |
Capacity as a regulator of the concentration of extracellular adenosine that is More ... |
GO:0008283 cell proliferation GO:0002376 immune system process GO:0045321 leukoc More ... |
Homo sapiens | Severe combined immunodeficiency due to ADA deficiency (omim:102700) | Pentostatin, Fludarabine, Dipyridamole, Cladribine | 3iar_A(100) | 3iar_A (100), 7rtg_A/B (100) | Phyre | 24933472 | ||
| P00883 | Aldolase EC:4.1.2.13 | Splits the fructose 1,6-bisphosphate, into dihydroxyacetone phosphate & glyceral More ... |
GO:0031674; C:I band; IEA:UniProtKB-SubCell. GO:0031430; C:M band; IEA:UniProtKB More ... |
Interacts with Wiskott-Aldrich Syndr. Protein (WASP) involved in controlling act More ... |
GO:0008150; P:biological_process. GO:0065007; P:biological regulation. GO:000367 More ... |
Oryctolagus cuniculus (Rabbit) | 1zah_A(100) | 1ado_A/B/C/D (100), 1ewd_A/B/C/D (100), 1ewe_A/B/C/D (100), 1ex5_A/B/C/D (100), More ... | Phyre | 23495010 | ||||
| P00924 | Enolase 1 EC: 4.2.1.11. | Glycolysis |
GO:0000324; C:fungal-type vacuole; IDA:SGD. GO:0005739; C:mitochondrion; IDA:SGD More ... |
Molecular chaperone |
GO:0008150 biological_process GO:0009987 cellular process GO:0006457 protein fol More ... |
Saccharomyces cerevisiae | 1ebg_A(100) | 1ebg_A/B (100), 1ebh_A/B (100), 1els_A (100), 1l8p_A/B/C/D (100), 1nel_A (100), More ... | Phyre | 22143554 | ||||
| P00957 | Alanine--tRNA ligase | Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine More ... |
GO:0005829; C:cytosol; IDA:UniProtKB. GO:0016020; C:membrane; IDA:UniProtKB. GO: More ... |
transcription regulator represses transcription of its own gene increased repres More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Escherichia coli | 1yfs_A(71) | 3hxu_A (100), 3hxv_A (100), 3hxw_A (100), 3hxx_A (100), 3hxy_A (100), 3hxz_A/B/C More ... | Phyre | 6264314 | ||||
| P00966 | Argininosuccinate synthase | Argininosuccinate synthase |
GO:0005737; C:cytoplasm; TAS:ProtInc. GO:0005829; C:cytosol; TAS:Reactome. GO:00 More ... |
RNA binding protein. Is indirectly involved in the control of blood pressure. |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compo More ... |
Homo sapiens | Citrullinemia 1 (CTLN1) (omim:215700) |
<a href=""https://www.drugbank.ca/biodb/bio_entities/BE0000671"">L-Arginine L-As More ... |
2nz2_A(100) | 2nz2_A (100) | Phyre | 26520658 | ||
| P01029 | Complement C4-B | Non-enzymatic component of C3 and C5 convertases and thus essential for the prop More ... |
GO:0030424; C:axon; ISO:MGI. GO:0072562; C:blood microparticle; ISO:MGI. GO:0030 More ... |
Mediate synapse elimination during postnatal development |
GO:0008150 biological_process GO:0009987 cellular process GO:0023052 signaling G More ... |
Mus musculus | 1hzf_A(80) | Phyre | 26814963 | |||||
| P01033 | Erythroid-potentiating activity | Stimulates the proliferation of Erythroid progenitor cells |
GO:0005604; C:basement membrane; IEA:Ensembl. GO:0070062; C:extracellular exosom More ... |
Tissue inhibitor of metalloproteinases 1 |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Homo sapiens | retinal degeneration (omim:305370) | 3v96_A(99) | 1d2b_A (100), 1oo9_B (100), 1uea_B/D (100), 2j0t_D/E/F (100), 3ma2_B/C (100), 3v More ... | Phyre | 6332112 | |||
| P02359 | S7 | Ribosomal protein |
GO:0005829; C:cytosol; IDA:EcoCyc. GO:0022627; C:cytosolic small ribosomal subun More ... |
Autogenous regulation of translation |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0045182; F:tr More ... |
Escherichia coli | 3j9y_g(100) | 1eg0_D (100), 1ml5_J (100), 2ykr_G (100), 3j5s_I (100), 3j9y_G (100), 3j9z_SG (1 More ... | Phyre | 6206783 | ||||
| P02362 | S8 (40S ribosomal protein S7) | Ribosomal protein |
GO:0005840; C:ribosome; IEA:UniProtKB-KW. GO:0003735; F:structural constituent o More ... |
When S8 is phosphorilated is an oocyte peripheral membrane protein associated wi More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Xenopus laevis | 3j7p_SH(97) | 7oyc_H2 (100) | Phyre | 1730756 | ||||
| P02401 | P2 (60S acidic ribosomal protein P2) | Ribosomal protein |
GO:0022625; C:cytosolic large ribosomal subunit; IDA:RGD. GO:0030687; C:preribos More ... |
P2 was isolated from the liver as an iron-binding protein that is responsible fo More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Rattus norvegicus | 4beh_B(97) | Phyre | 1524426 | |||||
| P02489 | alpha-crystallin A chain | Lens Crystallin |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0070062; C:extracellular exosome; IDA More ... |
Heat-shock protein |
GO:0008150 biological_process GO:0048519 negative regulation of biological proce More ... |
Homo sapiens | Cataract, Autoimmune diseases, Uveitis | Not available | 3l1e_A(93) | 6t1r_A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P (100) | Phyre | 9695791 | ||
| P02511 | alpha-crystallin B chain | Lens Crystallin |
GO:0032432; C:actin filament bundle; IEA:Ensembl. GO:0030424; C:axon; IEA:Ensemb More ... |
Heat-shock protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Homo sapiens | Myopathy, myofibrillar, fatal infantile hypertrophy, alpha-B crystallin-related More ... | 2klr_A(100) | 2klr_A/B (100), 2n0k_A/B (100), 2wj7_A/B/C/D/E (100), 2y1y_A (100), 2y1z_A/B (10 More ... | Phyre | 9695791 | |||
| P02730 | Band-3 anion exchanger | Its integral domain mediates a 1:1 exchange of inorganic anions across the membr More ... |
GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB. GO:0072562; C:blood mi More ... |
Regulator of glycolysis |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Homo sapiens | Renal tubular acidosis (omim:179800) | 4yzf_A(100) | 1bh7_A (100), 1bnx_A (100), 1btq_A (100), 1btr_A (100), 1bts_A (100), 1btt_A (10 More ... | Phyre | 8325839 | |||
| P03046 | Protein kil | Expression of the kil gene induces dramatic morphological changes in the host ce More ... | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | Inhibits bacterial cell division by disrupting FtsZ protofilaments and sequester More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0050789 regula More ... |
Bacteriophage Mu | Phyre | 26124275 | ||||||
| P03129 | Protein E7 | It is essential for cell transformation in cervical, oropharyngeal and other HPV More ... |
GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. GO:0042025; C:host cel More ... |
It is proposed to have a functional redox activity. Such an activity adds to the More ... |
GO:0003674 molecular_function GO:0044710 single-organism metabolic process GO:00 More ... |
Human Papillomavirus | 4yoz | 4yoz_B (100), 6apn_A/B (100), 7sqp_A/C (100), 7sr0_A/C (100), 7sr3_A/C (100), 7s More ... | Phyre | 24559112 | ||||
| P03880 | I-AniI maturase | Group I intron splicing factor |
GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. GO:0004519; F:endonuclease a More ... |
Homing endonuclease |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Aspergillus nidulans (Emericella nidulans) | 1p8k_Z(100) | 1p8k_Z (100), 2qoj_Z (100), 3eh8_A/D/G (100) | Phyre | 11991637 | ||||
| P04075 | Fructose-bisphosphate aldolase A | Plays a key role in glycolysis and gluconeogenesis. |
GO:0015629; C:actin cytoskeleton; IDA:BHF-UCL. GO:0005913; C:cell-cell adherens More ... |
ALDOA is located at the internal side of the plasma membrane or at the acrosomal More ... | Homo sapiens | Glycogen storage disease XII (omim:611881) | 1,6-Fructose Diphosphate, 1,3-Dihydroxyacetonephosphate, 1,6-DI-O-PHOSPHONO-D-MA More ... | 1zai_A(99) | 1ald_A (100), 2ald_A (100), 4ald_A (100), 5ky6_A/B/C/D (100), 6xmh_A/B (100), 6x More ... | Phyre | 23355646 | |||
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005829; C:cytosol; ISS:UniProtKB. GO More ... |
Uracil-DNA glycosylase, Transferrin receptor, involved in endocytosis, microtubu More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Homo sapiens | Huntington disease (omim:143100) | NADH, Adenosine-5-Diphosphoribose, Thionicotinamide-Adenine-Dinucleotide, 4-(2-A More ... | 1u8f_O(100) | 1u8f_O/P/Q/R (100), 1znq_O/P/Q/R (100), 3gpd_G/R (100), 4wnc_A/B/C/D/E/F/G/O (10 More ... | Phyre | 15877277 | ||
| P04637 | p53 | Nucleus/Transcription factor |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; IDA:UniProtKB. GO More ... |
Mitochondria/Promoting mitochondrial membrane permeabilization |
GO:0008150 biological_process GO:0065007 biological regulation GO:0007006 mitoch More ... |
Homo sapiens | Squamous cell carcinoma of the head and neck (HNSCC) (omim:275355) | Acetylsalicylic acid, AZD 3355, 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine | 3d06_A(99) | 1a1u_A/C (100), 1aie_A (100), 1c26_A (100), 1dt7_X/Y (100), 1gzh_A/C (100), 1h26 More ... | Phyre | 26499805 | ||
| P04642 | Lactate dehydrogenase | Lactate fermentation to pyruvate. |
GO:0005913; C:cell-cell adherens junction; IEA:Ensembl. GO:0005737; C:cytoplasm; More ... |
DNA maintenance | Rattus norvegicus | 4aj4_A(100) | 4aj1_A/B/C/D (100), 4aj2_A/B/C/D (100), 4aj4_A/B/C/D (100), 4aje_A/B/C/D (100), More ... | Phyre | 22143554 | |||||
| P04806 | Hexokinase EC:2.7.1.1 | Fructose and glucose phosphorylating enzyme (Glycolysis) |
GO:0005737; C:cytoplasm; IDA:SGD. GO:0005739; C:mitochondrion; IDA:SGD. GO:00055 More ... |
Transcriptional regulation |
GO:0008150;P:biological_process GO:0065007;P: biological regulation GO:0008152;P More ... |
Saccharomyces cerevisiae | 3b8a_X(100) | 1hkg_A (100), 3b8a_X (100) | Phyre | 12007644 | ||||
| P04818 | Thymidylate synthase EC:2.1.1.45 | Contributes to the de novo mitochondrial thymidylate biosynthesis pathway |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; TAS:Reactome. GO: More ... |
Translation inhibitor |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compoun More ... |
Homo sapiens | Breast neoplasm, Lung neoplasm, Ovarian neoplasm, Colonic neoplasm, Pancreatic n More ... | Irinotecan, Capecitabine, Floxuridine/5-fluorouracil, Flucytosine, Fluorouracil, More ... | 1hw3_A(100) | 1hvy_A/B/C/D (100), 1hw3_A (100), 1hw4_A (100), 1hzw_A/B (100), 1i00_A/B (100), More ... | Phyre | 1924359 | ||
| P05089 | Arginase EC:3.5.3.1 | Arginine hydrolysis |
GO:0005737; C:cytoplasm; TAS:ProtInc. GO:0005829; C:cytosol; TAS:Reactome. GO:00 More ... |
Potentially regulates arginine-dependent immune functions such as T lymphocyte a More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Argininemia (omim:207800) | L-Ornithine, 2(S)-Amino-6-Boronohexanoic Acid, Nor-N-Omega-Hydroxy-L-Arginine, D More ... | 1wva_A(100) | 1wva_A/B (100), 1wvb_A/B (100), 2aeb_A/B (100), 2pha_A/B (100), 2pho_A/B (100), More ... | Phyre | 20585552 | ||
| P05230 | FGF1 (Fibroblast growth factor 1) | Important role in the regulation of cell survival, cell division, angiogenesis, More ... |
GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. GO:0005829; C:cytosol; IDA:Uni More ... |
Stimulates cell adhesion and/or motility upon export, facilitating specific step More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Retinoblastoma (omim:180200) | Pentosan Polysulfate, Amlexanox, Sucrose Octasulfate, Formic Acid, O2-Sulfo-Gluc More ... | 1rml_A(100) | 1axm_A/B/C/D/E/F (100), 1djs_B (100), 1dzc_A (100), 1dzd_A (100), 1e0o_A/C (100) More ... | Phyre | 15998317 | ||
| P05388 | P0 | Ribosomal protein |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0036464; C:cytoplasmic ribonucleoprot More ... |
DNA repair | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | 3j92_s(100) | 4v6w_Q (100), 4v6x_CQ (100), 5aj0_AK (100), 6olg_AK (100), 6zm7_LS (100), 6zme_L More ... | Phyre | 1870984 | ||||
| P05455 | La protein (Lupus La protein) | Protect RNA from 3'-end digestion |
GO:0030529; C:intracellular ribonucleoprotein complex; TAS:ProtInc. GO:0000784; More ... |
RNA folding chaperone |
GO:0005524; F:ATP binding; GO:0006457; P:protein folding; |
Homo sapiens | Sjogren syndrome (omim:270150) | 1yty_A(100) | 1owx_A (100), 1s79_A (100), 1s7a_A (100), 1yty_A/B (100), 1zh5_A/B (100), 2vod_A More ... | Phyre | 16799560 | |||
| P05979 | Prostaglandin G/H synthase 1 | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid More ... |
GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0005789; C:endoplasmic reticulum memb More ... |
Peroxidase and cyclooxygenase |
GO:0003674 molecular_function GO:0044710 single-organism metabolic process GO:00 More ... |
Ovis aries | 2ayl_A(100) | 1cqe_A/B (100), 1diy_A (100), 1ebv_A (100), 1eqg_A/B (100), 1eqh_A/B (100), 1fe2 More ... | Phyre | 8248182 | ||||
| P06168 | Acetohydroxy acid reductoisomerase (ILV5) EC:1.1.1.86 | Catalyzes a step in branched-chain amino acid biosynthesis |
GO:0042645; C:mitochondrial nucleoid; IDA:SGD. GO:0005739; C:mitochondrion; IDA: More ... |
Maintenance of rho and mitochondrial DNA (& implication in the distribution of m More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | Phyre | 12136009 | ||||||
| P06396 | Gelsolin | Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) e More ... |
GO:0030478; C:actin cap; IDA:UniProtKB. GO:0015629; C:actin cytoskeleton; TAS:Pr More ... |
Controlling apoptosis | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Amyloidosis, Finnish type (omim:105120) | Latrunculin A | 3ffn_A(100) | 1c0f_S (100), 1c0g_S (100), 1d4x_G (100), 1dej_S (100), 1eqy_S (100), 1esv_S (10 More ... | Phyre | 22143554 | ||
| P06653 | Autolysin, LytA | Autolysins are involved in some important biological processes such as cell sepa More ... |
GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0008745; F:N-acety More ... |
Inhibits C3 convertase formation and reduces opsonization by iC3b |
GO:0008150 biological_process GO:0065007 biological regulation GO:0002376 immune More ... |
Streptococcus pneumoniae | 4iwt_A(94) | 1gvm_A/B/C/D/E/F (100), 1h8g_A/B (100), 1hcx_A/B (100), 2bml_A/B (100), 4ivv_A ( More ... | Phyre | 28265264 | ||||
| P06733 | Alpha-enolase | Glycolysis |
GO:0099738; C:cell cortex region; IDA:CAFA. GO:0009986; C:cell surface; IDA:CAFA More ... |
"Growth control, hypoxia tolerance and allergic responses. May also function in More ... |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compoun More ... |
Homo sapiens | Hashimoto encephalopathy | 2psn_A(100) | 2psn_A/B/C/D (100), 3b97_A/B/C/D (100), 5jlz_E/F (100), 5lax_E/F (100), 5ni9_C ( More ... | Phyre | 26520658 | |||
| P06744 | Phosphoglucose isomerase EC:5.3.1.9 | Catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate (glyco More ... |
GO:0060170; C:ciliary membrane; IEA:Ensembl. GO:0005737; C:cytoplasm; IDA:HPA. G More ... |
Neuroleukin, autocrine motility factor, differentiation and maturation factor / More ... |
GO:0003674 molecular_function GO:0050794 regulation of cellular process GO:00230 More ... |
Homo sapiens | Hemolytic anemia (omim:613470) | Alpha-D-Glucose-6-Phosphate, 6-Phosphogluconic Acid, 5-Phospho-D-Arabinohydroxam More ... | 1iri_A(100) | 1iat_A (100), 1iri_A/B/C/D (100), 1jiq_A/B/C/D (100), 1jlh_A/B/C/D (100), 1nuh_A More ... | Phyre | 3352744 | ||
| P06745 | Glucose-6-phosphate isomerase | Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor- More ... |
GO:0060170; C:ciliary membrane; IDA:MGI. GO:0005737; C:cytoplasm; ISO:MGI. GO:00 More ... |
Cytokine growth factor | Mus musculus | 1u0e_A(100) | 1u0e_A/B (100), 1u0f_A/B (100), 1u0g_A/B (100), 2cvp_A/B (100), 2cxn_A/B (100), More ... | Phyre | 2154192 | |||||