| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q9K498 | CYP170A1 (Cytochrome P450 170A1) | It Catalyzes the two-step allylic oxidation of epi-isozizaene to albaflavenone ( More ... |
GO:0005886; C:plasma membrane; IBA:GO_Central. GO:0020037; F:heme binding; IBA:G More ... |
Terpene synthase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Streptomyces coelicolor | 3dbg_A(100) | 3dbg_A/B (100), 3el3_A/B (100) | Phyre | 19858213 | ||||
| Q9KGU0 | Beta-galactosidase | Beta-galactosidase activity |
GO:0005618; C:cell wall; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular regi More ... |
Deglycosylate complement components |
GO:0008150 biological_process GO:0065007 biological regulation GO:0002376 immune More ... |
Streptococcus pneumoniae | Phyre | 28265264 | ||||||
| Q9KJ23 | 60 kDa chaperonin | Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Adhesin, binds to mucins and epithelial cells | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Lactobacillus johnsonii | 1iok_A(66) | Phyre | 17379720 | |||||
| Q9KK62 | Bile salt hydrolase | Choloylglycine hydrolase activity |
GO:0003674;F:molecular_function GO:0003824;F: catalytic activity GO:0016787 hydr More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bifidobacterium lactis | 2hez_A/B (100), 2hf0_A/B (100), 8esi_A/B/C/D/E/F/G/H (100), 8ete_A/B (100) | Phyre | 17557824 | |||||
| Q9KKF0 | 60 kDa chaperonin | Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Adhesin. | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Clostridium difficile | 4v4o_A(70) | Phyre | 22143554 | |||||
| Q9MB58 | 6-Phosphofructo-2-kinase–fructose-2,6-bisphosphatase (FKFBP) EC:2.7.1.105 | Sucrose and starch metabolism |
GO:0005829; C:cytosol; IDA:TAIR. GO:0005886; C:plasma membrane; IDA:TAIR. GO:000 More ... |
Plant-unique, N-terminal sequence required to form homotetramer and affects kine More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0065008 regula More ... |
Arabidopsis thaliana | 1c7z_A(65) | Phyre | 11672433 | |||||
| Q9NQX3 | Gephyrin, protein anchor | Microtubule-associated protein involved in membrane protein-cytoskeleton interac More ... |
GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0005737; C:cytoplasm; IBA:GO_C More ... |
Synthesis of molybdenum cofactor (MoCo). Copley et al.: it forms a scaffold bene More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0043167 ion binding GO:00431 More ... |
Homo sapiens | Molybdenum cofactor deficiency C (omim:615501) | Formic Acid, Imidazole, Propanoic Acid | 1t3e_A(100) | 1jlj_A/B/C (100) | Phyre | 9990024 | ||
| Q9P2J5 | Leucine--tRNA ligase, cytoplasmic | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two More ... |
GO:0005737; C:cytoplasm; IDA:HPA. GO:0005829; C:cytosol; IBA:GO_Central. GO:0005 More ... |
GTPase-activating protein (GAP) senses intracellular leucing concentration and b More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | Infantile liver failure syndrome 1 (omim:615438) | L-Leucine | 2wfd_A(100) | 2wfd_A/B (100), 6kid_A (100), 6kie_A (100), 6kqy_A (100), 6kr7_A (100), 6lpf_A/B More ... | Phyre | 22424946 | ||
| Q9RA63 | Chaperone protein ClpB | Part of a stress-induced multi-chaperone system |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Metalloprotease EC:3.4.24.87 |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Thermus thermophilus | 1qvr_A(100) | 1qvr_A/B/C (100), 4fct_A (100), 4fcv_A/B/C (100), 4fcw_A/C/F (100), 4fd2_A/B/D ( More ... | Phyre | 9149530 | ||||
| Q9SA18 | Aspartate-kinase–homoserine-dehydrogenase (AK–HSDH) EC:1.1.1.3 | Aspartate metabolism |
GO:0009507; C:chloroplast; IDA:TAIR. GO:0009570; C:chloroplast stroma; IDA:TAIR. More ... |
Homoserine dehydrogenase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Arabidopsis thaliana | 1ebf_A(74) | Phyre | 12602885 | |||||
| Q9SQT8 | 3-Dehydroquinatedehydratase–shikimate-NADP-oxidoreductase (DHQase—SORase) EC:1.1 More ... | Aromatic amino acidsynthesis |
GO:0009507; C:chloroplast; IDA:TAIR. GO:0009570; C:chloroplast stroma; IDA:TAIR. More ... |
Catalyzes third and fourth steps of pathway; tomato transcript is differentially More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Arabidopsis thaliana | 2gpt_A(100) | 2gpt_A (100), 2o7q_A (100), 2o7s_A (100), 6bmb_A (100), 6bmq_A (100) | Phyre | 11299368 | ||||
| Q9T071 | Hexokinase EC:2.7.1.1 | Fructose and glucose phosphorylating enzyme (Glycolysis) |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0016021; C:integral component of membr More ... |
Glucose signaling / Porine binding, Apoptosis / (In Eukaryotes binds to mitochon More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Arabidopsis thaliana | 4qs7_A(67) | Phyre | 12690200 | |||||
| Q9UAE6 | Enolase | 2-phospho-D-glycerate = phosphoenolpyruvate + H2O. |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Specifically binds to a TTTTCT DNA motif present in the cyst matrix antigen 1 (T More ... |
GO:0003674 molecular_function GO:0005488 binding GO:1901363 heterocyclic compoun More ... |
Toxoplasma gondii | 3otr_A(100) | Phyre | 25760592 | |||||
| Q9UH91 | Xanthine oxidoreductase | Purine catabolism enzyme |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0016491; F:oxidoreductase activity; ID More ... |
Structural role in the mammary gland |
GO:0008150 biological_process GO:0044767 single-organism developmental process G More ... |
Homo sapiens | XANTHINURIA, TYPE I (omim:278300) | 3nvv_A(85) | ITasser | 12502743 | ||||
| Q9UIU0 | Dihydropyridine receptor alpha 2 subunit | Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Chann More ... |
GO:0005886; C:plasma membrane; TAS:Reactome. GO:0061337; P:cardiac conduction; T More ... |
Can activate or inhibit native skeletal ryanodine receptors. |
GO:0003674 molecular_function GO:0006810 transport GO:0055085 transmembrane tran More ... |
Homo sapiens | 5gjv_F(98.5) | Phyre | 12620094 | |||||
| Q9UKX7 | Nuclear pore complex protein Nup50 | Component of the nuclear pore complex that has a direct role in nuclear protein More ... |
GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. GO:0031965; C:n More ... |
Interacts with regulatory proteins of cell cycle progression including CDKN1B (B More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding [Inf More ... |
Homo sapiens | 2EC1 | 2ec1_A (100), 3tj3_C/D (100), 7mo0_B/D (100) | Phyre | 26791761 | ||||
| Q9UQE7 | SMC3 (Sister chromatin cohesion) | Structural maintenance of chromosomes protein 3 |
GO:0005604; C:basement membrane; TAS:ProtInc. GO:0000785; C:chromatin; IDA:UniPr More ... |
Basement membrane bamacan (basement membrane chondroitin sulfate proteoglycan co More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0097367 carbohydrate derivat More ... |
Mus musculus | 2wd5_B(100) | 6wg3_B (100), 6wg4_B (100), 6wg6_B/D/F/H/J/L (100), 6wge_B (100), 7w1m_B (100), More ... | Phyre | 10375619 | ||||
| Q9URB4 | Fructose bisphosphate aldolase | Glycolysis, gluconeogenesis |
GO:0009986; C:cell surface; IDA:CGD. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubC More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Candida albicans | 1b57_A(68) | 6lnk_A/B (100), 7v6f_A/B (100), 7v6g_A/B (100), 7yva_A/B (100) | Phyre | 16371651 | ||||
| Q9V1F2 | DNA primase EC:3.1.1.29 | It is a type of RNA polymerase which creates an RNA primer |
GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW. GO:1990077; C:primosome More ... |
DNA and RNA polymerase |
GO:0003674 molecular_function GO:0003824 catalytic activity GO:0016740 transfe More ... |
Pyrococcus abyssi | Phyre | 17991487 | ||||||
| Q9VU87 | Vacuolar protein-sorting-associated protein 36 | Component of the ESCRT-II complex (ensodomal sorting complex required for transp More ... |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005768; C:endosome; ISS:UniProtKB. G More ... |
With other members of the ESCRT complex, binds to the localization element in th More ... |
GO:2000241 regulation of reproductive process GO:0060811 intracellular mRNA loca More ... |
Drosphila melanogaster | 2zme_B(66.6) | Phyre | 17268469 | |||||
| Q9XDS7 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus anginosus | 1w6t_A(94) | Phyre | 9603964 | |||||
| Q9Y3E5 | Pth2/Bit1 peptidyl-tRNA hydrolase 2/Bcl-2 inhibitor of transcription 1 EC:3.1.1. More ... | Peptidyl-tRNA hydrolase 2 |
GO:0005829; C:cytosol; IMP:UniProtKB. GO:0016020; C:membrane; IDA:UniProtKB. GO: More ... |
Inhibitor of transcription |
GO:0005654; C:nucleoplasm; IDA:HPA. GO:0003677; F:DNA binding; IEA:InterPro. GO: More ... |
Homo sapiens | Osteoarthritis (omim:601469) | 1q7s_A(100) | 1q7s_A/B (100) | Phyre | 14660562 | |||
| Q9Y5Y2 | Cytosolic Fe-S cluster assembly factor NUBP2 | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. More ... |
GO:0005814; C:centriole; IEA:UniProtKB-SubCell. GO:0005929; C:cilium; IEA:UniPro More ... |
It is thought that Nubp1 and Nubp2 proteins interact with each other and regulat More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0071840 cellul More ... |
Homo sapiens | 3vx3_A(60) | Phyre | 10486206 | |||||
| Q9Y697 | Cysteine desulfurase, mitochondrial | Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It s More ... |
GO:0005829; C:cytosol; IDA:HGNC. GO:0005759; C:mitochondrial matrix; IDA:HGNC. G More ... |
May be involved in the biosynthesis of molybdenum cofactor. |
GO:0005829; C:cytosol; IDA:HGNC. GO:0005759; C:mitochondrial matrix; IDA:HGNC. G More ... |
Homo sapiens | <a href=""https://www.drugbank.ca/biodb/bio_entities/BE0000151"">Pyridoxal Phosp More ... | 1p3w_A(67) | 5kz5_1/2/3/4/M/N/O/P/Q/R/S/T (100), 5usr_A/C/E/G (100), 5wgb_A (100), 5wkp_A/E ( More ... | Phyre | 28284029 | |||
| Q9Y6I3 | Epsin | Generating membrane curvature |
GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell. GO:0005737; C:cytoplas More ... |
Organizing mitotic membranes/influencing spindle assembly | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | 1h0a_A(100) | 1inz_A (100), 1kyd_P (100) | Phyre | 19704019 | ||||
| Q9Y7F0 | Tsa1p (Peroxiredoxin TSA1) EC:1.11.1.15 | Thiol-specific antioxidant-likeprotein |
GO:0009986; C:cell surface; IDA:CGD. GO:0005737; C:cytoplasm; IDA:CGD. GO:000927 More ... |
Chaperone / has been found in a genetic screen to be involved in mutation suppre More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Candida albicans | 3sbc_A(74) | Phyre | 16102003 | |||||
| Q9YE01 | Bifunctional phosphoglucose/phosphomannose isomerase |
Embden–Meyerhof pathway. |
GO:0030246; F:carbohydrate binding; IEA:InterPro. GO:0004347; F:glucose-6-phosph More ... |
Phosphomannose isomerase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Aeropyrum pernix | Phyre | 14551194 | ||||||
| Q9Z5C7 | Ribonucleoside-diphosphate reductase subunit beta | Ribonucleotide-diphosphate reductase |
GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro. GO:000 More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Staphylococcus aureus | 4bmo_A(57) | Phyre | 12062412 | |||||
| Q9Z7C9 | 60 kDa chaperonin 2 | Chaperone |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Implicated in initiation of chlamydial infection. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Chlamydia trachomatis | 1we3_A(63) | Phyre | 7682281 | |||||
| Q9ZCX6 | PPI (Peptidyl Prolyl cis,trans-Isomerase (PPI) EC:5.2.1.8) | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomeriza More ... |
GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell. GO:0003755; F:peptidyl More ... |
Adhesion to host, unknow receptor. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Rickettsia prowazekii | Phyre | 15230349 | ||||||
| Q9ZPI5 | Fatty acid multifunctional protein (MFP) EC:1.1.1.35 | Involved in peroxisomal fatty acid beta-oxidation during seed germination |
GO:0005618; C:cell wall; IDA:TAIR. GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCe More ... |
Bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA bio More ... |
GO:0008150 biological_process GO:0009987 cellular process GO:0008152 metabolic p More ... |
Arabidopsis thaliana | 2wtb_A(100) | 2wtb_A (100) | Phyre | 12586899 | ||||
| Q9ZUY3 | Arogenate dehydratase 3, chloroplastic | Converts the prephenate produced from the shikimate-chorismate pathway into phen More ... |
GO:0009507;C:chloroplast GO:0009570;C:chloroplast stroma GO:0005829;C:cytosol GO More ... |
Chloroplast division or transcriptional regulation, |
GO:0008150 biological_process GO:0009987 cellular process GO:0008152 metabolic p More ... |
Arabidopsis thaliana | Phyre | 28338876 | ||||||
| Q9ZVD5 | Protein argonaute 4 | Component of the RISC complex RNA-directed DNA methylation, involves small inter More ... |
GO:0015030; C:Cajal body; IDA:TAIR. GO:0030529; C:intracellular ribonucleoprotei More ... |
Cleaves RNA transcripts, enzyme generates small interfering RNAs (siRNAs) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Arabidopsis thaliana | 4ola_A(66) | Phyre | 16998468 | |||||
| Q9ZVR7 | Phytosulfokine receptor 1 | Serine/threonine-protein kinase activity |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. GO:0005886; C:pl More ... |
Guanylate cyclase activity |
GO:0003674;molecular_functionGO:0009165 nucleotide biosynthetic process GO:00061 More ... |
Arabidopsis thaliana | 4oac_A(60) | 4z63_A (100), 4z64_A (100) | Phyre | 25245092 | ||||
| R8AM44 | 60 kDa chaperonin | Chaperone |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:U More ... |
Adhesion to host, unknow receptor. |
GO:0008150 biological_process GO:0022610 biological adhesion |
Plesiomonas shigelloides | 4pkn_A(92) | Phyre | 17172512 | |||||
| S0B8V4 | Enolase | Glycolysis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Involved in the encystation mechanism |
GO:0008150 biological_process GO:0022610 biological adhesion GO:0007155 cell ad More ... |
Entamoeba invadens | 3qtp_A(90) | Phyre | 16170762 | |||||
| S4RG79 | Enolase | Glycolisis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Tau lens crystallin. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005198; F:st More ... |
Petromyzon marinus | 2psn_A(85) | Phyre | 4007081 | |||||
| T1TFA0 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Adhesion to host. It is an Effective Protective Antigen in Mice. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Streptococcus iniae | 3zlf_A(98) | Phyre | 26121302 | |||||
| T1WGD6 | Enolase | Glycolisis |
GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:mag More ... |
Binding to plasminogen. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Taenia pisiformis | 2psn_A(79) | Phyre | 25623259 | |||||
| U2XJZ2 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus anginosus | Phyre | 9603964 | ||||||
| U2Z425 | Glyceraldehyde-3-phosphate dehydrogenase | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004365; F:glyceraldehyde-3-p More ... |
Binding to Plasminogen |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus anginosus | Phyre | 24833341 | ||||||
| U2Z6L8 | ,3-bisphosphoglycerate-dependent phosphoglycerate mutase | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate | GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity More ... | Binding to plasmin(ogen) |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus anginosus | Phyre | 18310038 | ||||||
| V9W1Z1 | Enolase EC:4.2.1.11 | Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
A role in virulence: it could be involved in larval degradation, maybe through p More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Paenibacillus larvae subsp. larvae | 4a3r_A(79) | Phyre | 20609532 | |||||
| W0TYC8 | PgsE protein | It is a membrane-associated protein that is crucial for Extrachromosomal DNA mai More ... |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. GO:0016874; F:li More ... |
It functions in the declustering and/or partitioning of episomes. |
GO:0008150 biological_process GO:0065007 biological regulation GO:0009987 cellul More ... |
Bacillus subtilis | Phyre | 23583563 | ||||||