Displaying 551 - 600 of 694
Uni Prot Protein Name Long Description Canonical Function GO Moonlighting Function GO Moon Organism Human Disease Drugs Induction PDBs PDB UniProt Models Reference
Q5ZTY3 Chaperone protein DnaK Chaperone GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
GO:0006457; P:protein folding; I More ...
Adhesion to host, unknow receptor. GO:0008150 biological_process
GO:0051704 multi-organism process
GO:0044419 inter More ...
Legionella pneumophila 1dkg_D(83) Phyre 10231011
Q5ZXP3 60 kDa chaperonin Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ...
Adhesin. May play a protective role against the defense mechanisms generated by More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Legionella pneumophila 1aon_A(77) Phyre 17379720
Q6FGJ9 Glutathione S-transferase M3 (GSTM) Detoxification enzyme GO:0035686; C:sperm fibrous sheath; IEA:Ensembl.
GO:0004364; F:glutathione trans More ...
Sperm head proteins
involved in zona pellucida binding
GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens 3gtu_B(100) Phyre 23355646
Q6FGX3 Rab6A Retrograde transport from early endosomes to ER GO:0005622; C:intracellular; IEA:GOC.
GO:0005525; F:GTP binding; IEA:InterPro.
G More ...
1. Inactivation of spindle checkpoint; 2. Rab6C required for cell cycle progress More ... GO:0008150 biological_process
GO:0050789 regulation of biological process
GO:00 More ...
Homo sapiens 4dkx_A(99) Phyre 16395330
Q6GIL6 Triose phosphate isomerase EC:5.3.1.1 Catalyzes the reversible interconversion of dihydroxyacetone phosphate and D-gly More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004807; F:triose-phosphate i More ...
Adhesion to fungal mannans GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Staphylococcus aureus subsp. aureus 3m9y_A(100) 3m9y_A/B (100), 3uwu_A/B (100), 3uwv_A/B (100), 3uww_A/B (100), 3uwy_A/B (100), More ... Phyre 19423633
Q6L047 Glucose/galactose 1-dehydrogenase Catalyzes the NAD(P)+-dependent oxidation of D-glucose to D-gluconate via glucon More ... GO:0047910; F:galactose 1-dehydrogenase (NADP+) activity; IDA:UniProtKB.
GO:0005 More ...
Is also significantly active with D-galactose as substrate, but not with D-xylos More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0003824; F:ca More ...
3wic_A(69.3) Phyre 15691337
Q6NVH9 GAL3 (Galectin 3) Lectin, Galactosidase-binding, soluble GO:0016936; F:galactoside binding Induction of T-cell apoptosis; cell adhesion/migration GO:0008150 biological_process
GO:0022610 biological adhesion
GO:0007155 cell adh More ...
Homo sapiens 1kjl_A(99) Phyre 15375548
Q6PJ79 Intersectin (ISTN2) Involved in clathrin-mediated endocytosis GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA: More ...
Orienting mitotic spindle via cdc42 GEF activity GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0030234; F:en More ...
Homo sapiens 2khn_A(74) Phyre 20479469
Q6Q3I2 Alcohol acetaldehyde dehydrogenase Acetaldehyde dehydrogenase (acetylating) activity - alcohol dehydrogenase (NAD) More ... GO:0008774; F:acetaldehyde dehydrogenase (acetylating) activity; IEA:InterPro.
G More ...
Binding to Caco-2 cells & Binding to eukaryotic Hsp60 GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Listeria monocytogenes 3zdr_A(79) Phyre 16499624
Q6T267 Isocitrate lyase Glyoxylate cycle GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0005622; C:intracellular; ID More ...
Growth GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Aspergillus fumigatus 1dqu_A(88) Phyre 25566229
Q6YBU6 Serum opacity factor Opacifies mammalian serum. GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. Fibronectin binding protein. Is a streptococcal virulence factor which binds to More ... GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0 More ...
Streptococcus pyogenes Phyre 20671930
Q6YP21 Kynurenine--oxoglutarate transaminase 3 Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynur More ... GO:0005739; C:mitochondrion; IEA:Ensembl.
GO:0047804; F:cysteine-S-conjugate bet More ...
RNA binding protein. May catalyze the beta-elimination of S-conjugates and Se-c More ... GO:0003674 molecular_function
GO:0005488 binding
GO:1901363 heterocyclic compo More ...
Homo sapiens <a href=""https://www.drugbank.ca/biodb/bio_entities/BE0002162"">Pyridoxal Phosp More ... 3e2y_A(86) Phyre 26520658
Q704D1 2-dehydro-3-deoxy-D-gluconate/2-dehydro-3-deoxy-phosphogluconate aldolase Involved in the degradation of glucose via the Entner-Doudoroff pathway. Catalyz More ... GO:0061677; F:2-dehydro-3-deoxy-D-gluconate aldolase activity; IEA:UniProtKB-EC. More ... It is not able to use 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3- More ... GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase More ...
Thermoproteus tenax 2r91_A(100) 2r91_A/B/C/D (100), 2r94_A/B/C/D (100) Phyre 12824170
Q70YI1 Outer membrane protein MIP Essential virulence factor associated with macrophage infectivity. GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl More ...
PPIase activity. Binds to collagen IV in the extracellular matrix. GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Legionella pneumophila 1fd9_A(100) Phyre 25870856
Q71UF1 Aconitase EC:4.2.1.3 Catalyses the Stereo-specific isomerization of citrate to isocitrate via cis-aco More ... GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulf More ...
Doom homeostasis / IREBP: Iron-responsive element-binding protein (cytosol), mtD More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens Infantile cerebellar-retinal degeneration (omim:614559) 1b0j_A(96) Phyre 8041788
Q745I2 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase Splits the fructose 1,6-bisphosphate, into dihydroxyacetone phosphate & glyceral More ... GO:0047443; F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity; IEA:UniProtKB More ... M. avium adhesins bind to intestinal mucus aldolase, conceivably facilitating in More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Mycobacterium avium subsp. paratuberculosis 1nxj_A(88) Phyre 15207805
Q74JU6 Elongation factor Tu Elongation factor in protein synthesis GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:U More ...
Attachment to human cells and mucin (Binding to intestinal epithelial cells and More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Lactobacillus johnsonii Phyre 15039339
Q75NZ0 Ferredoxin: sulfite reductase (Fd–SiR) EC:1.8.7.1 Sulfite reductase activity (thus involved in development and growth) GO:0042644; C:chloroplast nucleoid; IDA:UniProtKB.
GO:0009570; C:chloroplast str More ...
Chloroplast DNA compacting protein GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Pea (Pisum sativum). And soybean, tobacco and probably Arabidopsis 5h8v_A(77) Phyre 11997391
Q77E16 E6 oncoprotein Oncoprotein GO:0044204; C:host cell nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA More ...
Recruits P53 to an E6 protein complex that ubiquitinates P53 for degradation; it More ... GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0030234; F:en More ...
Human papillomavirus type 16 4xr8_F(95) Phyre 21963854
Q7L0Y3 Mitochondrial RNase P Functions in mitochondrial tRNA maturation (Part of mitochondrial ribonuclease P More ... GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0042645; C:mitochondrial nu More ...
The endonuclease removing tRNA 5' extensions, is a methyltransferase GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0003824; F:ca More ...
Homo sapiens 5nfj_A/B/C (100), 7onu_F (100), 8cbk_F (100), 8cbl_F (100), 8cbm_F (100), 8cbo_E More ... Phyre 23042678
Q7LX99 Trex (Alpha-1,4-Transferase) Glycogen debranching enzyme (Trehalose biosynthesis) GO:0004133; F:glycogen debranching enzyme activity; IEA:InterPro.
GO:0004553; F: More ...
Alpha-1,6-Glucosidase GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase More ...
Sulfolobus solfataricus 2vnc_A(100) Phyre 18703518
Q7LYI9 Glucose 1-dehydrogenase 1 Catalyzes the NAD(P)+-dependent oxidation of D-glucose to D-gluconate via glucon More ... GO:0047936; F:glucose 1-dehydrogenase [NAD(P)] activity; IEA:UniProtKB-HAMAP.
GO More ...
Galactose
dehydrogenase
GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0003824; F:ca More ...
Sulfolobus solfataricus 2cd9_A(100) Phyre 12824170
Q7YQK6 Upsilon-crystallin EC:1.1.1.27 Lens crystallin GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0004459; F:L-lactate dehydrogenase act More ...
Lactate dehydrogenase A GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0003824; F:ca More ...
Ornithorhynchus anatinus (Duckbill platypus) 5kkc_A(94) Phyre 2462567
Q7YZX3 Enolase EC: 4.2.1.11. Glycolysis GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
GO:0000287; F:mag More ...
Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Onchocerca volvulus 2psn_A(71) Phyre 12818429
Q7Z4W1 L-xylulose reductase Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, More ... GO:0005903; C:brush border; IEA:Ensembl.
GO:0005881; C:cytoplasmic microtubule; More ...
A role in cell adhesion, pointing to a novel function involving tumour progressi More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens Pentosuria (omim:260800) Isopropyl Alcohol, Dihydrogenphosphate Ion, 2'-Monophosphoadenosine 5'-Diphospho More ... 1pr9_A(100) 1pr9_A/B (100), 1wnt_A/B/C/D (100), 3d3w_A/B (100) Phyre 24720935
Q81UL6 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0008886; F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylat More ... Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Bacillus anthracis 1euh_A(60) Phyre 22143554
Q81X74 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.17 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) More ... Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Bacillus anthracis 1gd1_O(79) Phyre 20727989
Q834N2 Pyruvate formate-lyase 1-activating enzyme Pyruvate formate lyase GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur c More ...
Associated with epithelial cell binding GO:0008150 biological_process
GO:0051704 multi-organism process
GO:0044419 inter More ...
Enterococcus faecalis Phyre 24362949
Q845Q5 Enolase Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
GO:0005576; C:extracellular r More ...
Is an immunosuppressive protein GO:0044414(suppression of host defenses)
GO:0032733(positive regulation of inter More ...
Streptococcus sobrinus 3zlf_A(95) Phyre 14678332
Q86U72 GAK Cyclin-G associated kinase / Auxilin 2 Uncoating clathrin-coated vesicles GO:0016301; F:kinase activity; IEA:UniProtKB-KW. 1. Promotes MT outgrowth during spindle assembly; 2. Centrosome cohesion GO:0008150 biological_process
GO:0006996 organelle organization
GO:0000226 micro More ...
Homo sapiens 1n4c_A(80) Phyre 20237935
Q86XF0 Bifunctional dihydrofolate reductase-thymidylate synthase Dihydrofolate reductase and Thymidylate synthase, enzyme 5,6,7,8-tetrahydrofolat More ... GO:0005743; C:mitochondrial inner membrane; IMP:UniProtKB.
GO:0005759; C:mitocho More ...
mRNA translation inhibition regulation of plasmodium TS-DHFR mRNA translation GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Homo sapiens Aminopterin, Chlorproguanil, MCB-3837, Pralatrexate, Proguanil, Proquanil, Pyrim More ... 1kmv_A(93) Phyre 11964483
Q88VE0 Elongation factor Tu This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:U More ...
Binding to intestinal epithelial cells, competitive exclusion and displacement o More ... GO:0008150 biological_process
GO:0051704 multi-organism process
GO:0044419 inter More ...
Lactobacillus plantarum 1efc_A(83) Phyre 18619532
Q88YH4 Triosephosphate isomerase D-glyceraldehyde 3-phosphate = glycerone phosphate. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004807; F:triose-phosphate i More ...
Binding to intestinal epithelial cells, competitive exclusion and displacement o More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Lactobacillus plantarum 3m9y_A(69) Phyre 18619532
Q88YH6 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) More ... Binding to Plasminogen.
Binding to fibronectin.
Binding to colonic, porcine or v More ...
GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Lactobacillus plantarum 4qx6_A(68) 8hmn_A/B/C/D (100) Phyre 17379720
Q8CJF8 ARGONAUTE4 (Protein argonaute-4) Directing Chromatin remodeling factors to a target locus GO:0005737; C:cytoplasm; ISO:MGI.
GO:0000932; C:cytoplasmic mRNA processing body More ...
Cleaving RNA transcripts to produce siRNAs GO:0008150 biological_process
GO:0008152 metabolic process
GO:0065007 biological More ...
Mus musculus 4kre_A(83) Phyre 16998468
Q8CPY5 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004365; F:glyceraldehyde-3-p More ...
Plasminogen binding. Transferrin-binding protein. GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Staphylococcus epidermidis 3k73_O(92) Phyre 17379720
Q8CX00 60 kDa chaperonin Chaperone GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ...
Located in the membrane surface. Putative virulence factor. GO:0008150 biological_process
GO:0051704 multi-organism process
GO:0044419 inter More ...
Streptococcus agalactiae 1fya_A(65) Phyre 11854208
Q8DNW9 Endopeptidase O Metalloendopeptidase activity GO:0008150 biological_process
GO:0008152 metabolic process
GO:0006807 nitrogen c More ...
Activates and depletes complement. Inhibits C3 convertase formation. GO:0002682 regulation of immune system process
GO:0080134 regulation of response More ...
Streptococcus pneumoniae 3zuk_A(64) Phyre 28265264
Q8DQX8 Phosphoglycerate kinase ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ...
Plasminogen binding and tPA activator.
Inhibits MAC formation and depletes compl More ...
GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Streptococcus pneumoniae 4dg5_A(76) Phyre 24196407
Q8DR54 6PGD (6-phosphogluconate dehydrogenase) EC:1.1.1.44 Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phos More ... GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:Uni More ... Putative adhesin GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Streptococcus pneumoniae 2iyo_A(75) Phyre 16634799
Q8DTS9 Enolase EC: 4.2.1.11. Glycolysis GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
GO:0005576; C:extracellular r More ...
Plasminogen binding. Binding to salivary mucin. GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Streptococcus mutans 5boe_A(84) Phyre 17964283
Q8DXS8 Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... GO:0051287; F:NAD binding; IEA:InterPro.
GO:0050661; F:NADP binding; IEA:InterPr More ...
Immunomodulator (is reported to function as a virulence factor with B lymphocyte More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Streptococcus agalactiae 3gnq_A(100) Phyre 17237385
Q8DXT0 Phosphoglycerate kinase ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:U More ...
Binding to plasmin(ogen) and binding to actin GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Streptococcus agalactiae Phyre 21729749
Q8G5N9 Phosphoglycerate mutase ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. GO:0016853; F:isomerase activity; IEA:UniProtKB-KW Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Bifidobacterium longum Phyre 17557824
Q8G6W1 Chaperone protein DnaK Acts as a chaperone. GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
GO:0006457; P:protein folding; I More ...
Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Bifidobacterium animalis 1yuw_A(73) Phyre 20167618
Q8GE63 Enolase EC:4.2.1.11 Conversion of 2-phosphoglycerate to phosphoenolpyruvate (Glycolysis) GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
GO:0005576; C:extracellular r More ...
Plasminogen binding GO:0003674; F:molecular_function. Synonyms: molecular function.
GO:0005488; F:bi More ...
Aeromonas hydrophila 3h8a_A(91) Phyre 19270100
Q8GX14 Glutamineamidotransferase–glutamine-cyclase (GATase–GNC) Histidine synthesis GO:0009507; C:chloroplast; IDA:TAIR.
GO:0009570; C:chloroplast stroma; IDA:TAIR. More ...
Catalyzes fifth and sixth steps of pathway (imidazole ring synthesis); substrate More ... GO:0008152; P:metabolic process. Synonyms: metabolism; metabolic process resulti More ... Arabidopsis thaliana Phyre 9654139
Q8IWX2 RHAMM mitotic spindle/hyaluronan-binding protein GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
GO:0007155; P:cell adhesion More ...
Extracellular RHAMM-CD44 partnering sustains CD44 surface display and enhances C More ... GO:0008150 biological_process
GO:0008152 metabolic process
GO:0065007 biologica More ...
Homo sapiens Venous thromboembolism (omim:188050) 5gky_A(73) Phyre 18354082
Q8IXV0 Hes 1 protein Transcriptional repressor GO:0005654; C:nucleoplasm; IDA:HPA.
GO:0003677; F:DNA binding; IEA:InterPro.
GO: More ...
It is able to induce the activation of the NF-kB (Nuclear factor-kappaB) pathway More ... GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Homo sapiens Leukemia, myeloid/lymphoid or mixed-lineage (omim:159555) 2mh3_A(100) Phyre 20832754
Q8KP52 60 kDa chaperonin Chaperone GO:0005524; F:ATP binding; IEA:InterPro. Adhesin GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... Listeria monocytogenes 4v4o_A(67) Phyre 14742538