| Uni Prot | Protein Name | Long Description | Canonical Function | GO | Moonlighting Function | GO Moon | Organism | Human Disease | Drugs | Induction | PDBs | PDB UniProt | Models | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P78545 | ETS-related transcription factor Elf-3 | Transcriptional activator that binds and transactivates ETS sequences containing More ... |
GO:0005829; C:cytosol; IDA:HPA. GO:0005794; C:Golgi apparatus; IDA:HPA. GO:00056 More ... |
Involved in mediating vascular inflammation. May play an important role in epith More ... |
GO:0097190 apoptotic signaling pathway GO:0035556 intracellular signal transduct More ... |
Homo sapiens | Cancer | 3jtg_A(100) | 2e8p_A (100) | Phyre | 26499805 | |||
| P82612 | Phosphoglycerate mutase | Phosphoglyceromutase |
GO:0097311; C:biofilm matrix; IDA:CGD. GO:0009986; C:cell surface; IDA:CGD. GO:0 More ... |
Plasminogen binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Candida albicans | 1qhf_A(79) | Phyre | 12622818 | |||||
| P84022 | Mothers against decapentaplegic homolog 3 | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and More ... |
GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005829; C:cytosol; IDA:HPA. GO:00007 More ... |
Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TG More ... |
GO:0003674 molecular_function GO:0005488 binding GO:0060090 binding, bridging GO More ... |
Homo sapiens | Colorectal cancer (CRC) (omim:114500) | 1khx_A(97) | 1mhd_A/B (100), 1mjs_A (100), 1mk2_A (100), 1ozj_A/B (100), 1u7f_A/C (100), 2laj More ... | Phyre | 26499805 | |||
| P92980 | 5'-adenylylsulfate reductase 3, chloroplastic (50-Adenylylphosphosulfatereductas More ... | Sulfate assimilation |
GO:0009507; C:chloroplast; IDA:TAIR. GO:0051539; F:4 iron, 4 sulfur cluster bind More ... |
Catalyzes committing step for sulfate reduction (versus sulfation pathway) | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Arabidopsis thaliana | 2goy_A(78) | Phyre | 8917600 | |||||
| P94915 | Glyceraldehyde-3-phosphate dehydrogenase | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004365; F:glyceraldehyde-3-p More ... |
EGF-receptor |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium avium | 2g82_A(64) | Phyre | 8757813 | |||||
| P99136 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004365; F:glyceraldehyde-3-p More ... |
Transferrin receptor. Binding to Plasminogen. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0060089; F:mo More ... |
Staphylococcus aureus | 3k73_O(100) | Phyre | 10785640 | |||||
| P99999 | Cytochrome c | It transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and More ... |
GO:0005829; C:cytosol; IMP:UniProtKB. GO:0005743; C:mitochondrial inner membrane More ... |
Controlling apoptosis | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Homo sapiens | Thrombocytopaenia (omim:612004) | Minocycline, Protoporphyrin Ix Containing Co, Heme C, Imidazole, Protoporphyrin More ... | 1j3s_A(100) | 1j3s_A (100), 2n3y_A (100), 2n9i_A (100), 2n9j_A (100), 3nwv_A/B/C/D (100), 3zcf More ... | Phyre | 15907471 | ||
| P9WGE9 | Superoxide dismutase [Cu-Zn] | Destroys radicals which are normally produced within the cells and which are tox More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005576; C:extracellular region; IDA:MT More ... |
Adhesin, binding to a number of host moonlighting proteins such as Glyceraldehyd More ... |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1pzs_A(100) | 1pzs_A (100) | Phyre | 14687559 | ||||
| P9WK17 | Malate synthase G | Malate synthase activity, Magnesium & Manganesium ion binding |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005829; C:cytosol; IDA:MTBBASE. GO:000 More ... |
Laminin/fibronectin binding protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1n8i_A(100) | 2gq3_A/B (100), 3s9i_A (100), 3s9z_A (100), 3sad_A (100), 3saz_A (100), 3sb0_A ( More ... | Phyre | 16677310 | ||||
| P9WMJ9 | Chaperone protein DnaK | Chaperone: Prevents misfolding and promotes the refolding and proper assembly o More ... |
GO:0097691; C:bacterial extracellular vesicle; IDA:UniProtKB. GO:0042603; C:caps More ... |
Stimulates CD8 lymphocyte chemokine production - Stimulates monocyte chemokine s More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0050789 regula More ... |
Mycobacterium tuberculosis | 4rtf_D(100) | 6w6e_I (100), 7l6n_I/J/K (100), 7o00_CCC (100), 8gb3_D (100) | Phyre | 10671216 | ||||
| P9WN39 | Glutamine Synthetase | Glutamine synthetase ATP + L-glutamate + NH3 => ADP + phosphate + L-glutamine |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005829; C:cytosol; IDA:MTBBASE. GO:000 More ... |
Plasminogen and fibronectin binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 4xyc_A(100) | 1hto_A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X (100), 1htq_A/B/C/D/E/F/G/H More ... | Phyre | 17849409 | ||||
| P9WN83 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.26 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005829; C:cytosol; IDA:MTBBASE. GO:000 More ... |
EGF-receptor |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1hdg_O(62) | 8br4_A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P (100) | Phyre | 8757813 | ||||
| P9WNL1 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005618; C:cell wall; IDA: More ... |
Binds to plasminogen. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 4rop_A(69) | 6l7d_A (100), 7ckp_A (100), 7clk_A (100), 7cll_A/B/C/D (100), 7dlr_A (100), 7e4f More ... | Phyre | 27569900 | ||||
| P9WP65 | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA | Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005737; C:cytoplasm; IEA:UniProtKB-Sub More ... |
Controls cell wall permeability | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Mycobacterium tuberculosis | 3ib7_A(100) | 2hy1_A (100), 2hyo_A (100), 2hyp_A (100), 3ib7_A (100), 3ib8_A (100) | Phyre | 19801656 | ||||
| P9WPE7 | 60 kDa chaperonin 2 | Chaperone: Prevents misfolding and promotes the refolding and proper assembly of More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005829; C:cytosol; IDA:MTBBASE. GO:000 More ... |
Activates monocyte cytokine synthesis - Cell surface protein involved in macroph More ... | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Mycobacterium tuberculosis | 3rtk_A(100) | 1sjp_A/B (100), 3rtk_A/B (100) | Phyre | 8419086 | ||||
| P9WPE9 | 60 kDa chaperonin 1 | Prevents misfolding and promotes the refolding and proper assembly of unfolded p More ... |
GO:0043590; C:bacterial nucleoid; IDA:MTBBASE. GO:0009986; C:cell surface; IEA:U More ... |
Biofilm formation Granuloma Formation DNA binding |
GO:0008150 biological_process GO:0009987 cellular process GO:0051704 multi-organ More ... |
Mycobacterium tuberculosis | 3m6c_A(100) | 3m6c_A (100) | Phyre | 25986150 | ||||
| P9WPW9 | Glutamate racemase | Glutamate racemase (Provides the (R)-glutamate required for cell wall biosynthes More ... |
GO:0005886; C:plasma membrane; IDA:MTBBASE. GO:0008657; F:DNA topoisomerase (ATP More ... |
DNA kinase inhibitor |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0030234; F:en More ... |
Mycobacterium tuberculosis | 5hj7_A(100) | 5hj7_A/B (100) | Phyre | 18757813 | ||||
| P9WPW9 | Glutamate racemase EC:5.1.1.3 | It provides D-glutamate, a key building block in the peptidoglycan of the bacter More ... |
GO:0005886; C:plasma membrane; IDA:MTBBASE. GO:0008657; F:DNA topoisomerase (ATP More ... |
Acts as an inhibitor of DNA gyrase |
GO:0003674 molecular_function GO:0003824 catalytic activity GO:0016787 hydrolase More ... |
Mycobacterium tuberculosis | 5hj7_A(100) | 5hj7_A/B (100) | Phyre | 18757813 | ||||
| P9WQN9 | Diacylglycerol acyltransferase/mycolyltransferase Ag85C | he antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005576; C:extracellular region; IDA:MT More ... |
fibronectin binding. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1sfr_A(82) | 1dqy_A (100), 1dqz_A/B (100), 1va5_A/B (100), 3hrh_A/B (100), 4mql_A (100), 4mqm More ... | Phyre | 2403534 | ||||
| P9WQP1 | Diacylglycerol acyltransferase/mycolyltransferase Ag85B | Transferase activity |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005576; C:extracellular region; IDA:MT More ... |
Fibronectin binding proteins |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1f0n_A(100) | 1f0n_A (100), 1f0p_A (100), 5trz_P/Q (100), 5ts1_P/Q/R/S (100) | Phyre | 16368974 | ||||
| P9WQP3 | Diacylglycerol acyltransferase/mycolyltransferase Ag85A | The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005737; C:cytoplasm; IEA:UniProtKB-Sub More ... |
Fibronectin binding. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1sfr_A(100) | 1sfr_A/B/C (100) | Phyre | 2403534 | ||||
| P9WQP3 | Diacylglycerol acyltransferase/mycolyltransferase Ag85A | They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alph More ... |
GO:0005618; C:cell wall; IDA:MTBBASE. GO:0005737; C:cytoplasm; IEA:UniProtKB-Sub More ... |
Binding of plasmi(ogen) & Binding to fibronectin, |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Mycobacterium tuberculosis | 1sfr_A(100) | 1sfr_A/B/C (100) | Phyre | 17849409 | ||||
| Q00488 | Chaperone protein DnaK | Chaperone |
GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. GO:0006457; P:protein folding; I More ... |
Adhesion to host, unknow receptor. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Mycobacterium avium | 1yuw_A(77) | Phyre | 9119453 | |||||
| Q00519 | Xanthine dehydrogenase/oxidase | Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xan More ... |
GO:0005829; C:cytosol; IBA:GO_Central. GO:0005615; C:extracellular space; ISO:MG More ... |
Structural role in milk secretion. |
GO:0048732 gland development GO:0050878 regulation of body fluid levels GO:00328 More ... |
Mus musculus | 3an1_A(94) | Phyre | 22143554 | |||||
| Q00610 | Clathrin | Membrane trafficking protein |
GO:0030118; C:clathrin coat; NAS:UniProtKB. GO:0030132; C:clathrin coat of coate More ... |
1. Stabilizing michrotubules in kinetochore fibers; 2. Nuclear function (not yet More ... |
GO:0008150 biological_process GO:0071840 cellular component organization or biog More ... |
Homo sapiens | 1xi4_A(100) | 2xzg_A (100), 4g55_A (100), 6e4l_A (100), 6qnn_A (100), 6qnp_A/B/C/D (100), 7bn1 More ... | Phyre | 3834033 | ||||
| Q01289 | NADPH: protochlorophyllide oxidoreductase (POR) EC:1.3.1.33 | Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide) |
GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. GO:0016630; F:protochlorophyll More ... |
Formation of prolamellar body | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Pea (Pisum sativum), Arabidopsis | Phyre | 11115885 | ||||||
| Q02155 | Hexokinase | Conversion of glucose to glucose 6-phosphate |
GO:0005623; C:cell; IEA:GOC. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:000 More ... |
Transcription regulation. Apoptosis. | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Plasmodium falciparum | 1bg3_A(70) | Phyre | 25580350 | |||||
| Q02252 | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial | Plays a role in valine and pyrimidine metabolism. |
GO:0070062; C:extracellular exosome; IDA:UniProtKB. GO:0005759; C:mitochondrial More ... |
Binds fatty acyl-CoA. Binds RNA. | GO:0003674 molecular_function GO:0005488 binding GO:0048037 cofactor binding GO: More ... | Homo sapiens | Methylmalonate semialdehyde dehydrogenase deficiency (MMSDHD) (omim:614105) | NADH | 1t90_A(57) | 8xxq_A/B/C/D (100), 9izu_C/D (100), 9izv_A/B/C/D (100), 9izw_A/B/C/D (100), 9izx More ... | Phyre | 26520658 | ||
| Q02T82 | Elongation factor Tu | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Factor H and plasminogen binding |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding |
Pseudonomas aeruginosa | 1efc_A(87) | Phyre | 17709513 | |||||
| Q04120 | Peroxiredoxin TSA2 | Reduces peroxides. May play an important role in eliminating peroxides generated More ... |
GO:0005737; C:cytoplasm; IDA:SGD. GO:0051920; F:peroxiredoxin activity; IDA:SGD. More ... |
Molecular chaperones helps proteins fold | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 5dvb_A(99) | 5dvb_A/B/C/D/E/F/G/H/I/J (100), 5ept_A/B/C/D/E/F/G/H/I/J (100), 6utl_A/B/C/D/E/F More ... | Phyre | 15163410 | ||||
| Q04360 | Nuclear protein BS-MLF1 (EBV-SM) | Down-regulation of intron-containing mRNA |
GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. GO:0042025; C:host cel More ... |
Up-regulation of intron-less mRNA |
GO:0008150 biological_process GO:0065007 biological regulation GO:0008152 metabo More ... |
Epstein–Barr virus | Phyre | 9671768 | ||||||
| Q043Z5 | Enolase | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruva More ... |
GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular r More ... |
Adhesion to host. | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Lactobacillus gasseri | 5boe_A(54) | Phyre | 25917402 | |||||
| Q04IN8 | Pneumolysin | Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol More ... |
GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0020002; C:host ce More ... |
Activates complement away from bacterial cells and depletes complement component More ... |
GO:0008150 biological_process GO:0065007 biological regulation GO:0002376 immune More ... |
Streptococcus pneumoniae | 5cr6_D(100) | 4zgh_A (100), 5aod_A (100), 5aoe_A/B (100), 5aof_A (100), 5cr6_D (100), 5cr8_A/D More ... | Phyre | 28265264 | ||||
| Q04N79 | Elongation factor Tu | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site More ... |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:U More ... |
Surface displayed human complement regulator binding protein. |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Streptococcus pneumoniae | 1exm_A(75) | Phyre | 25046156 | |||||
| Q05201 | Developmental protein eyes absent EC:3.1.3.48 | Transcription factor (control development drosophila eyes) |
GO:0005737; C:cytoplasm; IDA:FlyBase. GO:0005634; C:nucleus; IDA:UniProtKB. GO:0 More ... |
It has intrinsic protein Tyr phosphatase activity EC:3.1.3.48 |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Drosophila melanogaster | 3geb_A(67) | Phyre | 14628053 | |||||
| Q05762 | Dihydrofolate-reductasethymidylate-synthase (DHFR–TS) EC:1.5.1.3 | Tetrahydrofolate synthesis |
GO:0005829; C:cytosol; IDA:TAIR. GO:0004146; F:dihydrofolate reductase activity; More ... |
Thymidylate-synthase |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0003824; F:ca More ... |
Arabidopsis thaliana | 3ihi_A(69) | 8dae_A (100) | Phyre | 10737138 | ||||
| Q05G10 | Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.12 | Conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phos More ... |
GO:0051287; F:NAD binding; IEA:InterPro. GO:0050661; F:NADP binding; IEA:InterPr More ... |
Is involved in the adhesion to erythrocytes. |
GO:0008150 biological_process GO:0051704 multi-organism process GO:0044419 inter More ... |
Mycoplasma suis | 2ep7_A(69) | Phyre | 17336568 | |||||
| Q06559 | S3 | Ribosomal protein |
GO:0022626; C:cytosolic ribosome; IDA:FlyBase. GO:0022627; C:cytosolic small rib More ... |
DNA repair |
GO:0003674 molecular_function GO:0003824 catalytic activity GO:0016829 lyase act More ... |
Drosophila melanogaster | 4v6w_AD(100) | 4v6w_AD (100), 6xu6_AD (100), 6xu7_AD (100), 6xu8_AD (100) | Phyre | 7929231 | ||||
| Q07637 | Pyruvate kinase | This protein is involved in step 5 of the subpathway that synthesizes pyruvate f More ... |
GO:0009986; C:cell surface; IDA:CAFA. GO:0005524; F:ATP binding; IEA:UniProtKB-K More ... |
Binding to invertase |
GO:0003674 molecular_function GO:0005488 binding GO:0005515 protein binding GO:0 More ... |
Lactococcus lactis | 3hqn_A(65) | Phyre | 19898842 | |||||
| Q08438 | VHS3 - Phosphopantothenoylcysteine decarboxylase subunit VHS3 | Coenzyme A biosynthesis |
GO:1990143; C:CoA-synthesizing protein complex; IDA:SGD. GO:0071513; C:phosphopa More ... |
Halotolerance determinant | GO:0008150; P:biological_process. Synonyms: physiological process; biological pr More ... | Saccharomyces cerevisiae | 1e20_A(71) | Phyre | 19915539 | |||||
| Q0VCU1 | Aconitase EC:4.2.1.3 | Aconitase TCA cycle |
GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0051539; F:4 iron, 4 sulfur c More ... |
Iron responsive element binding protein |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Bos taurus | 2b3y_A(95) | Phyre | 1334546 | |||||
| Q10589 | Bone marrow stromal antigen 2 | Interferon-inducible restriction factor |
GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW. GO:0016324; C:ap More ... |
It also acts as a pattern recognition receptor inducing NF-κB-dependent pro More ... |
GO:0003674 molecular_function GO:0060089 molecular transducer activity GO:000487 More ... |
Homo sapiens | HIV-1 and murine leukemia virus infection (omim:600534) | 3mqb_A(100) | 2lk9_A (100), 2x7a_A/B/C/D/E/F/G/H/I/J/K (100), 2xg7_A/C (100), 3mq7_A/B/C/D/E/F More ... | Phyre | 24782851 | |||
| Q12309 | Clf1p pre-mRNA splicing factor | pre-mRNA splicing factor |
GO:0000785; C:chromatin; IDA:SGD. GO:0071011; C:precatalytic spliceosome; IBA:GO More ... |
Initiation of DNA replication |
GO:0003674 molecular_function GO:0005488 binding protein binding GO:1990935 spl More ... |
Saccharomyces cerevisiae | 5lj5_S(100) | 5gm6_D (100), 5gmk_D (100), 5lj3_S (100), 5lj5_S (100), 5lqw_R (100), 5mps_S (10 More ... | Phyre | 11102353 | ||||
| Q12904 | Aminoacyl tRNA synthase complex | Non-catalytic component of the multisynthase complex. Stimulates the catalytic a More ... |
GO:0017101; C:aminoacyl-tRNA synthetase multienzyme complex; IDA:CAFA. GO:000998 More ... |
Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signalin More ... |
GO:0010817 regulation of hormone levels GO:0032940 secretion by cell GO:0009914 More ... |
Homo sapiens | LEUKODYSTROPHY, HYPOMYELINATING (omim:260600) | 1fl0_A(100) | 1e7z_A (100), 1euj_A/B (100), 1fl0_A (100), 4r3z_A (100), 8j9s_A/B (100), 8ong_A More ... | Phyre | 25035493 | |||
| Q13485 | Mothers against decapentaplegic homolog 4 | In muscle physiology, plays a central role in the balance between atrophy and hy More ... |
GO:0032444; C:activin responsive factor complex; IDA:BHF-UCL. GO:0005813; C:cent More ... |
May act as a tumor suppressor. Positively regulates PDPK1 kinase activity by sti More ... |
GO:0003674 molecular_function GO:1901564 organonitrogen compound metabolic proce More ... |
Homo sapiens | Pancreatic cancer (PNCA) (omim:260350) | 1dd1_A(100) | 1dd1_A/B/C (100), 1g88_A/B/C (100), 1mr1_A/B (100), 1u7f_B (100), 1u7v_B (100), More ... | Phyre | 26499805 | |||
| Q13584 | Isocitrate dehydrogenase EC:1.1.1.42 | TCA cycle enzyme |
GO:0005739; C:mitochondrion; IDA:UniProtKB. GO:0004450; F:isocitrate dehydrogena More ... |
Mitochondrial mRNA binding |
GO:0003674; F:molecular_function. Synonyms: molecular function. GO:0005488; F:bi More ... |
Homo sapiens | GLIOBLASTOMA MULTIFORME (omim:137800) | 5svn_A(99) | Phyre | 7505425 | ||||
| Q15046 | Lysine--tRNA ligase | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 st More ... |
GO:0017101; C:aminoacyl-tRNA synthetase multienzyme complex; IEA:Ensembl. GO:000 More ... |
Cytokine binds to macrophages and peripheral blood mononuclear cells increases T More ... | Homo sapiens | Charcot-Marie-Tooth disease, recessive intermediate, B (omim:613641) | L-Lysine | 3bju_A(100) | 3bju_A/B/C/D (100), 4dpg_A/B/C/D/E/F/G/H (100), 4ycu_A/B (100), 4ycw_A/B/E/F (10 More ... | Phyre | 3988754 | |||
| Q15118 | Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Kinase that plays a key role in regulation of glucose and fatty acid metabolism More ... |
GO:0005759; C:mitochondrial matrix; TAS:Reactome. GO:0005967; C:mitochondrial py More ... |
"Acts as a key regulator of OIS (Oncogene-induced senescence) - The observation More ... |
GO:0008150 biological_process GO:0009987 cellular process GO:0032502 development More ... |
Homo sapiens | 2q8g_A(100) | 2q8f_A (100), 2q8g_A (100), 2q8h_A (100) | Phyre | 23685455 | ||||
| Q15311 | RLIP76 (RalA-binding protein 1 - RALBP1) | Binding partner of Ap-2, epsin and Numb in interphase |
GO:0005829; C:cytosol; TAS:Reactome. GO:0016020; C:membrane; IDA:UniProtKB. GO:0 More ... |
Mitotic spindle assembly |
GO:0008150 biological_process GO:0071840 cellular component organization or biog More ... |
Homo sapiens | Hypertension, Prostatic neoplasms, Myocardial Ischemia | Sorafenib, Vincristine, Carbamazepine, Doxorubicin | 2mbg_A(100) | 2kwh_A (100), 2kwi_B (100), 2mbg_A (100), 6zqt_C/D (100), 6zrn_C/D (100) | Phyre | 9973605 | ||
| Q15723 | ETS-related transcription factor | Nucleus/Morphology and terminal differentiation |
GO:0005737; C:cytoplasm; IDA:HPA. GO:0005654; C:nucleoplasm; IDA:HPA. GO:0005634 More ... |
Cytoplasm/Transformation |
GO:0050794 regulation of cellular process GO:0048522 positive regulation of cel More ... |
Homo sapiens | Cancer | 1bc8_C(56) | Phyre | 26499805 | ||||